1 00:00:07,110 --> 00:00:12,629 first class off 2 00:00:12,629 --> 00:00:12,639 3 00:00:12,639 --> 00:00:15,600 our proteins and the proteins are 4 00:00:15,600 --> 00:00:15,610 our proteins and the proteins are 5 00:00:15,610 --> 00:00:20,010 our proteins and the proteins are obtained from the amino acid monomers 6 00:00:20,010 --> 00:00:20,020 obtained from the amino acid monomers 7 00:00:20,020 --> 00:00:24,240 obtained from the amino acid monomers and let's look at these I'm gonna amino 8 00:00:24,240 --> 00:00:24,250 and let's look at these I'm gonna amino 9 00:00:24,250 --> 00:00:30,139 and let's look at these I'm gonna amino acids in closer let's take for example 10 00:00:30,139 --> 00:00:30,149 acids in closer let's take for example 11 00:00:30,149 --> 00:00:46,080 acids in closer let's take for example this amino acids alright this is an 12 00:00:46,080 --> 00:00:46,090 this amino acids alright this is an 13 00:00:46,090 --> 00:00:49,800 this amino acids alright this is an amino acid this is the carboxylic group 14 00:00:49,800 --> 00:00:49,810 amino acid this is the carboxylic group 15 00:00:49,810 --> 00:00:53,850 amino acid this is the carboxylic group right and this is the amine part this is 16 00:00:53,850 --> 00:00:53,860 right and this is the amine part this is 17 00:00:53,860 --> 00:00:57,900 right and this is the amine part this is simple hydrogen and that is the alkyl 18 00:00:57,900 --> 00:00:57,910 simple hydrogen and that is the alkyl 19 00:00:57,910 --> 00:00:58,470 simple hydrogen and that is the alkyl group 20 00:00:58,470 --> 00:00:58,480 group 21 00:00:58,480 --> 00:01:01,260 group it could be hydrogen or I'll kill any 22 00:01:01,260 --> 00:01:01,270 it could be hydrogen or I'll kill any 23 00:01:01,270 --> 00:01:04,289 it could be hydrogen or I'll kill any alkyl groups here again as you see if 24 00:01:04,289 --> 00:01:04,299 alkyl groups here again as you see if 25 00:01:04,299 --> 00:01:07,010 alkyl groups here again as you see if this R is not equal to the hydrogen 26 00:01:07,010 --> 00:01:07,020 this R is not equal to the hydrogen 27 00:01:07,020 --> 00:01:09,899 this R is not equal to the hydrogen which is a glycine the simplest amino 28 00:01:09,899 --> 00:01:09,909 which is a glycine the simplest amino 29 00:01:09,909 --> 00:01:16,050 which is a glycine the simplest amino acids the amino acids are optically 30 00:01:16,050 --> 00:01:16,060 acids the amino acids are optically 31 00:01:16,060 --> 00:01:19,110 acids the amino acids are optically active there must be chiral why because 32 00:01:19,110 --> 00:01:19,120 active there must be chiral why because 33 00:01:19,120 --> 00:01:22,200 active there must be chiral why because we have a carbon and to this carbon four 34 00:01:22,200 --> 00:01:22,210 we have a carbon and to this carbon four 35 00:01:22,210 --> 00:01:25,740 we have a carbon and to this carbon four different bonds group actually bonded to 36 00:01:25,740 --> 00:01:25,750 different bonds group actually bonded to 37 00:01:25,750 --> 00:01:29,730 different bonds group actually bonded to that carbon means make that amino acid 38 00:01:29,730 --> 00:01:29,740 that carbon means make that amino acid 39 00:01:29,740 --> 00:01:32,340 that carbon means make that amino acid optically active actually optically 40 00:01:32,340 --> 00:01:32,350 optically active actually optically 41 00:01:32,350 --> 00:01:32,940 optically active actually optically active 42 00:01:32,940 --> 00:01:32,950 active 43 00:01:32,950 --> 00:01:36,840 active now these chiral molecules and these 44 00:01:36,840 --> 00:01:36,850 now these chiral molecules and these 45 00:01:36,850 --> 00:01:39,870 now these chiral molecules and these enantiomers one we said rotates the 46 00:01:39,870 --> 00:01:39,880 enantiomers one we said rotates the 47 00:01:39,880 --> 00:01:41,550 enantiomers one we said rotates the plane polarized light to the left 48 00:01:41,550 --> 00:01:41,560 plane polarized light to the left 49 00:01:41,560 --> 00:01:44,010 plane polarized light to the left certain angle the other one rotates a 50 00:01:44,010 --> 00:01:44,020 certain angle the other one rotates a 51 00:01:44,020 --> 00:01:45,690 certain angle the other one rotates a plane polarized right to the right 52 00:01:45,690 --> 00:01:45,700 plane polarized right to the right 53 00:01:45,700 --> 00:01:49,440 plane polarized right to the right certain angle and so the one which 54 00:01:49,440 --> 00:01:49,450 certain angle and so the one which 55 00:01:49,450 --> 00:01:52,620 certain angle and so the one which rotates to the right is termed by simply 56 00:01:52,620 --> 00:01:52,630 rotates to the right is termed by simply 57 00:01:52,630 --> 00:01:55,980 rotates to the right is termed by simply D the one which rotates to the left is 58 00:01:55,980 --> 00:01:55,990 D the one which rotates to the left is 59 00:01:55,990 --> 00:01:59,219 D the one which rotates to the left is called L so the optically active or 60 00:01:59,219 --> 00:01:59,229 called L so the optically active or 61 00:01:59,229 --> 00:02:02,580 called L so the optically active or chiral molecule enantiomers one of the 62 00:02:02,580 --> 00:02:02,590 chiral molecule enantiomers one of the 63 00:02:02,590 --> 00:02:03,890 chiral molecule enantiomers one of the energy members is called 64 00:02:03,890 --> 00:02:03,900 energy members is called 65 00:02:03,900 --> 00:02:09,059 energy members is called deform the capital D actually I should 66 00:02:09,059 --> 00:02:09,069 deform the capital D actually I should 67 00:02:09,069 --> 00:02:16,140 deform the capital D actually I should say deform or al form and L is the one 68 00:02:16,140 --> 00:02:16,150 say deform or al form and L is the one 69 00:02:16,150 --> 00:02:18,240 say deform or al form and L is the one rotates the plane polarized light to the 70 00:02:18,240 --> 00:02:18,250 rotates the plane polarized light to the 71 00:02:18,250 --> 00:02:20,369 rotates the plane polarized light to the left D is the one rotates plane 72 00:02:20,369 --> 00:02:20,379 left D is the one rotates plane 73 00:02:20,379 --> 00:02:23,339 left D is the one rotates plane polarized right to the right right we 74 00:02:23,339 --> 00:02:23,349 polarized right to the right right we 75 00:02:23,349 --> 00:02:24,430 polarized right to the right right we have two 76 00:02:24,430 --> 00:02:24,440 have two 77 00:02:24,440 --> 00:02:28,540 have two that again so that means that amino 78 00:02:28,540 --> 00:02:28,550 that again so that means that amino 79 00:02:28,550 --> 00:02:32,710 that again so that means that amino acids will have a D and al for now the 80 00:02:32,710 --> 00:02:32,720 acids will have a D and al for now the 81 00:02:32,720 --> 00:02:36,940 acids will have a D and al for now the interesting things again all amino acids 82 00:02:36,940 --> 00:02:36,950 interesting things again all amino acids 83 00:02:36,950 --> 00:02:43,330 interesting things again all amino acids in living organisms are al for only 84 00:02:43,330 --> 00:02:43,340 in living organisms are al for only 85 00:02:43,340 --> 00:02:47,800 in living organisms are al for only there are few but bacteria have the D 86 00:02:47,800 --> 00:02:47,810 there are few but bacteria have the D 87 00:02:47,810 --> 00:02:51,400 there are few but bacteria have the D form of the amino acids very few 88 00:02:51,400 --> 00:02:51,410 form of the amino acids very few 89 00:02:51,410 --> 00:02:53,650 form of the amino acids very few actually but all of them are al form not 90 00:02:53,650 --> 00:02:53,660 actually but all of them are al form not 91 00:02:53,660 --> 00:02:56,920 actually but all of them are al form not the D form how for one enantiomer is a 92 00:02:56,920 --> 00:02:56,930 the D form how for one enantiomer is a 93 00:02:56,930 --> 00:02:58,330 the D form how for one enantiomer is a matter of fact okay 94 00:02:58,330 --> 00:02:58,340 matter of fact okay 95 00:02:58,340 --> 00:03:01,480 matter of fact okay now let's look at this again this is the 96 00:03:01,480 --> 00:03:01,490 now let's look at this again this is the 97 00:03:01,490 --> 00:03:03,430 now let's look at this again this is the this is the let me write it down 98 00:03:03,430 --> 00:03:03,440 this is the let me write it down 99 00:03:03,440 --> 00:03:13,230 this is the let me write it down carboxylic acid carboxylic acid part and 100 00:03:13,230 --> 00:03:13,240 carboxylic acid carboxylic acid part and 101 00:03:13,240 --> 00:03:24,700 carboxylic acid carboxylic acid part and this is the amine group and this is 102 00:03:24,700 --> 00:03:24,710 this is the amine group and this is 103 00:03:24,710 --> 00:03:27,610 this is the amine group and this is simply the alkyl group 104 00:03:27,610 --> 00:03:27,620 simply the alkyl group 105 00:03:27,620 --> 00:03:30,960 simply the alkyl group it could be alkyl or other group in fact 106 00:03:30,960 --> 00:03:30,970 it could be alkyl or other group in fact 107 00:03:30,970 --> 00:03:37,900 it could be alkyl or other group in fact alkyl or other groups again and this 108 00:03:37,900 --> 00:03:37,910 alkyl or other groups again and this 109 00:03:37,910 --> 00:03:41,530 alkyl or other groups again and this carbon which is next to the carboxylic 110 00:03:41,530 --> 00:03:41,540 carbon which is next to the carboxylic 111 00:03:41,540 --> 00:03:44,820 carbon which is next to the carboxylic acid carbonyl carbon is called alpha 112 00:03:44,820 --> 00:03:44,830 acid carbonyl carbon is called alpha 113 00:03:44,830 --> 00:03:48,330 acid carbonyl carbon is called alpha carbon this is called simply alpha 114 00:03:48,330 --> 00:03:48,340 carbon this is called simply alpha 115 00:03:48,340 --> 00:03:54,790 carbon this is called simply alpha carbon carbon and this amino acids which 116 00:03:54,790 --> 00:03:54,800 carbon carbon and this amino acids which 117 00:03:54,800 --> 00:03:56,920 carbon carbon and this amino acids which has the amine group attached to the 118 00:03:56,920 --> 00:03:56,930 has the amine group attached to the 119 00:03:56,930 --> 00:03:58,740 has the amine group attached to the Alpha carbon are called 120 00:03:58,740 --> 00:03:58,750 Alpha carbon are called 121 00:03:58,750 --> 00:04:07,360 Alpha carbon are called alpha amino acids alpha amino acids all 122 00:04:07,360 --> 00:04:07,370 alpha amino acids alpha amino acids all 123 00:04:07,370 --> 00:04:13,530 alpha amino acids alpha amino acids all four amino acids now when we simply 124 00:04:13,530 --> 00:04:13,540 four amino acids now when we simply 125 00:04:13,540 --> 00:04:18,250 four amino acids now when we simply polymerize this amino acids by peptide 126 00:04:18,250 --> 00:04:18,260 polymerize this amino acids by peptide 127 00:04:18,260 --> 00:04:20,710 polymerize this amino acids by peptide link it's actually condensation 128 00:04:20,710 --> 00:04:20,720 link it's actually condensation 129 00:04:20,720 --> 00:04:22,390 link it's actually condensation polymerization by giving one water 130 00:04:22,390 --> 00:04:22,400 polymerization by giving one water 131 00:04:22,400 --> 00:04:25,840 polymerization by giving one water molecule out and forming another carbon 132 00:04:25,840 --> 00:04:25,850 molecule out and forming another carbon 133 00:04:25,850 --> 00:04:28,690 molecule out and forming another carbon simply nitrogen bond which we call that 134 00:04:28,690 --> 00:04:28,700 simply nitrogen bond which we call that 135 00:04:28,700 --> 00:04:32,650 simply nitrogen bond which we call that peptide bond we end up with proteins 136 00:04:32,650 --> 00:04:32,660 peptide bond we end up with proteins 137 00:04:32,660 --> 00:04:36,279 peptide bond we end up with proteins proteins now again how big these 138 00:04:36,279 --> 00:04:36,289 proteins now again how big these 139 00:04:36,289 --> 00:04:37,370 proteins now again how big these proteins there 140 00:04:37,370 --> 00:04:37,380 proteins there 141 00:04:37,380 --> 00:04:40,340 proteins there Fareway very large very big molecules 142 00:04:40,340 --> 00:04:40,350 Fareway very large very big molecules 143 00:04:40,350 --> 00:04:45,230 Fareway very large very big molecules the average again I can't say exactly 144 00:04:45,230 --> 00:04:45,240 the average again I can't say exactly 145 00:04:45,240 --> 00:04:47,720 the average again I can't say exactly but the molecular weights like five 146 00:04:47,720 --> 00:04:47,730 but the molecular weights like five 147 00:04:47,730 --> 00:04:50,930 but the molecular weights like five hundred thousand atomic mass units 148 00:04:50,930 --> 00:04:50,940 hundred thousand atomic mass units 149 00:04:50,940 --> 00:04:53,510 hundred thousand atomic mass units sometimes million atomic mass units and 150 00:04:53,510 --> 00:04:53,520 sometimes million atomic mass units and 151 00:04:53,520 --> 00:04:59,900 sometimes million atomic mass units and so on very large big molecules now there 152 00:04:59,900 --> 00:04:59,910 so on very large big molecules now there 153 00:04:59,910 --> 00:05:06,380 so on very large big molecules now there are again twenty-two amino acids I guess 154 00:05:06,380 --> 00:05:06,390 are again twenty-two amino acids I guess 155 00:05:06,390 --> 00:05:09,860 are again twenty-two amino acids I guess has to be twenty-two over here one two 156 00:05:09,860 --> 00:05:09,870 has to be twenty-two over here one two 157 00:05:09,870 --> 00:05:12,530 has to be twenty-two over here one two three four five six seven eight nine 10 158 00:05:12,530 --> 00:05:12,540 three four five six seven eight nine 10 159 00:05:12,540 --> 00:05:17,510 three four five six seven eight nine 10 11 12 13 14 15 16 18 19 20 here we have 160 00:05:17,510 --> 00:05:17,520 11 12 13 14 15 16 18 19 20 here we have 161 00:05:17,520 --> 00:05:23,410 11 12 13 14 15 16 18 19 20 here we have 20 only 20 of those are found in human 162 00:05:23,410 --> 00:05:23,420 20 only 20 of those are found in human 163 00:05:23,420 --> 00:05:27,860 20 only 20 of those are found in human bodies again 20 of those but we have to 164 00:05:27,860 --> 00:05:27,870 bodies again 20 of those but we have to 165 00:05:27,870 --> 00:05:30,560 bodies again 20 of those but we have to remember that out of those 20 amino 166 00:05:30,560 --> 00:05:30,570 remember that out of those 20 amino 167 00:05:30,570 --> 00:05:34,760 remember that out of those 20 amino acids we can only synthesize our body 168 00:05:34,760 --> 00:05:34,770 acids we can only synthesize our body 169 00:05:34,770 --> 00:05:39,260 acids we can only synthesize our body can only synthesize 11 of those so that 170 00:05:39,260 --> 00:05:39,270 can only synthesize 11 of those so that 171 00:05:39,270 --> 00:05:42,920 can only synthesize 11 of those so that means that nine of the amino acids which 172 00:05:42,920 --> 00:05:42,930 means that nine of the amino acids which 173 00:05:42,930 --> 00:05:47,840 means that nine of the amino acids which we need have to be taken by food eaten 174 00:05:47,840 --> 00:05:47,850 we need have to be taken by food eaten 175 00:05:47,850 --> 00:05:49,370 we need have to be taken by food eaten the food that means they have to be 176 00:05:49,370 --> 00:05:49,380 the food that means they have to be 177 00:05:49,380 --> 00:05:53,240 the food that means they have to be ingested right ingested that's another I 178 00:05:53,240 --> 00:05:53,250 ingested right ingested that's another I 179 00:05:53,250 --> 00:05:56,990 ingested right ingested that's another I guess important things interesting too 180 00:05:56,990 --> 00:05:57,000 guess important things interesting too 181 00:05:57,000 --> 00:06:05,030 guess important things interesting too now the amino acids are simply combined 182 00:06:05,030 --> 00:06:05,040 now the amino acids are simply combined 183 00:06:05,040 --> 00:06:08,390 now the amino acids are simply combined by peptide links as we say here and form 184 00:06:08,390 --> 00:06:08,400 by peptide links as we say here and form 185 00:06:08,400 --> 00:06:11,750 by peptide links as we say here and form the polymers and the proteins let's read 186 00:06:11,750 --> 00:06:11,760 the polymers and the proteins let's read 187 00:06:11,760 --> 00:06:14,120 the polymers and the proteins let's read this slide here again amino acids have 188 00:06:14,120 --> 00:06:14,130 this slide here again amino acids have 189 00:06:14,130 --> 00:06:16,640 this slide here again amino acids have amino and carboxylic acid functional 190 00:06:16,640 --> 00:06:16,650 amino and carboxylic acid functional 191 00:06:16,650 --> 00:06:19,790 amino and carboxylic acid functional groups as we see here amino and the 192 00:06:19,790 --> 00:06:19,800 groups as we see here amino and the 193 00:06:19,800 --> 00:06:21,640 groups as we see here amino and the carboxylic acid functional groups 194 00:06:21,640 --> 00:06:21,650 carboxylic acid functional groups 195 00:06:21,650 --> 00:06:25,310 carboxylic acid functional groups proteins are polymers of alpha amino 196 00:06:25,310 --> 00:06:25,320 proteins are polymers of alpha amino 197 00:06:25,320 --> 00:06:28,790 proteins are polymers of alpha amino acids again alpha means the amine is 198 00:06:28,790 --> 00:06:28,800 acids again alpha means the amine is 199 00:06:28,800 --> 00:06:30,800 acids again alpha means the amine is bonded to the second carbon from this 200 00:06:30,800 --> 00:06:30,810 bonded to the second carbon from this 201 00:06:30,810 --> 00:06:34,310 bonded to the second carbon from this side here a condensation reaction 202 00:06:34,310 --> 00:06:34,320 side here a condensation reaction 203 00:06:34,320 --> 00:06:37,580 side here a condensation reaction between the amine end of one amino acid 204 00:06:37,580 --> 00:06:37,590 between the amine end of one amino acid 205 00:06:37,590 --> 00:06:41,510 between the amine end of one amino acid and the acid end of another produces the 206 00:06:41,510 --> 00:06:41,520 and the acid end of another produces the 207 00:06:41,520 --> 00:06:45,050 and the acid end of another produces the peptide bond and this is called peptide 208 00:06:45,050 --> 00:06:45,060 peptide bond and this is called peptide 209 00:06:45,060 --> 00:06:47,710 peptide bond and this is called peptide link or peptide bond which is an amide 210 00:06:47,710 --> 00:06:47,720 link or peptide bond which is an amide 211 00:06:47,720 --> 00:06:50,210 link or peptide bond which is an amide linkage okay let's 212 00:06:50,210 --> 00:06:50,220 linkage okay let's 213 00:06:50,220 --> 00:06:54,200 linkage okay let's to simply look at this and see how we 214 00:06:54,200 --> 00:06:54,210 to simply look at this and see how we 215 00:06:54,210 --> 00:06:58,250 to simply look at this and see how we can get the peptide lane now 216 00:06:58,250 --> 00:06:58,260 can get the peptide lane now 217 00:06:58,260 --> 00:07:01,790 can get the peptide lane now the amino acid this amino acids is also 218 00:07:01,790 --> 00:07:01,800 the amino acid this amino acids is also 219 00:07:01,800 --> 00:07:05,470 the amino acid this amino acids is also found in this form to this part is 220 00:07:05,470 --> 00:07:05,480 found in this form to this part is 221 00:07:05,480 --> 00:07:08,750 found in this form to this part is acidic part right this is the acid and 222 00:07:08,750 --> 00:07:08,760 acidic part right this is the acid and 223 00:07:08,760 --> 00:07:12,620 acidic part right this is the acid and remember a mean is the basic part it has 224 00:07:12,620 --> 00:07:12,630 remember a mean is the basic part it has 225 00:07:12,630 --> 00:07:14,560 remember a mean is the basic part it has that electron pair which makes it loose 226 00:07:14,560 --> 00:07:14,570 that electron pair which makes it loose 227 00:07:14,570 --> 00:07:18,860 that electron pair which makes it loose base and can accept the protons and the 228 00:07:18,860 --> 00:07:18,870 base and can accept the protons and the 229 00:07:18,870 --> 00:07:21,650 base and can accept the protons and the amino acids can be found in this form to 230 00:07:21,650 --> 00:07:21,660 amino acids can be found in this form to 231 00:07:21,660 --> 00:07:26,290 amino acids can be found in this form to this amino acids are and here is co all 232 00:07:26,290 --> 00:07:26,300 this amino acids are and here is co all 233 00:07:26,300 --> 00:07:34,060 this amino acids are and here is co all - and hydrogen and here we have nh3 plus 234 00:07:34,060 --> 00:07:34,070 - and hydrogen and here we have nh3 plus 235 00:07:34,070 --> 00:07:38,150 - and hydrogen and here we have nh3 plus the ionic form of the amino acids this 236 00:07:38,150 --> 00:07:38,160 the ionic form of the amino acids this 237 00:07:38,160 --> 00:07:43,280 the ionic form of the amino acids this is simply called sua turian iron again 238 00:07:43,280 --> 00:07:43,290 is simply called sua turian iron again 239 00:07:43,290 --> 00:07:46,940 is simply called sua turian iron again right so that hydrogen can be here or 240 00:07:46,940 --> 00:07:46,950 right so that hydrogen can be here or 241 00:07:46,950 --> 00:07:49,520 right so that hydrogen can be here or can be there as a matter of fact so this 242 00:07:49,520 --> 00:07:49,530 can be there as a matter of fact so this 243 00:07:49,530 --> 00:07:52,550 can be there as a matter of fact so this is the ionic form of the amino acids 244 00:07:52,550 --> 00:07:52,560 is the ionic form of the amino acids 245 00:07:52,560 --> 00:07:55,490 is the ionic form of the amino acids amino acids let's look at again how we 246 00:07:55,490 --> 00:07:55,500 amino acids let's look at again how we 247 00:07:55,500 --> 00:08:15,709 amino acids let's look at again how we form the peptide linkage peptide bond 248 00:08:15,709 --> 00:08:15,719 249 00:08:15,719 --> 00:08:31,009 okay let's take this amino acids the 250 00:08:31,009 --> 00:08:31,019 okay let's take this amino acids the 251 00:08:31,019 --> 00:08:41,170 okay let's take this amino acids the ionic form and this is actually glycine 252 00:08:41,170 --> 00:08:41,180 ionic form and this is actually glycine 253 00:08:41,180 --> 00:08:46,400 ionic form and this is actually glycine simplest amino acid glycine this is the 254 00:08:46,400 --> 00:08:46,410 simplest amino acid glycine this is the 255 00:08:46,410 --> 00:08:48,740 simplest amino acid glycine this is the hydrogen you see again the R group in 256 00:08:48,740 --> 00:08:48,750 hydrogen you see again the R group in 257 00:08:48,750 --> 00:08:51,129 hydrogen you see again the R group in this case is hydrogen simplest one and 258 00:08:51,129 --> 00:08:51,139 this case is hydrogen simplest one and 259 00:08:51,139 --> 00:09:03,139 this case is hydrogen simplest one and let's combine that with this another 260 00:09:03,139 --> 00:09:03,149 let's combine that with this another 261 00:09:03,149 --> 00:09:19,249 let's combine that with this another amino acids and this is alanine and this 262 00:09:19,249 --> 00:09:19,259 amino acids and this is alanine and this 263 00:09:19,259 --> 00:09:22,129 amino acids and this is alanine and this is abbreviated by G for example only 264 00:09:22,129 --> 00:09:22,139 is abbreviated by G for example only 265 00:09:22,139 --> 00:09:26,059 is abbreviated by G for example only this is abbreviated as a like this now 266 00:09:26,059 --> 00:09:26,069 this is abbreviated as a like this now 267 00:09:26,069 --> 00:09:28,429 this is abbreviated as a like this now the condensation reaction polymerization 268 00:09:28,429 --> 00:09:28,439 the condensation reaction polymerization 269 00:09:28,439 --> 00:09:32,679 the condensation reaction polymerization reactions again as followed we get this 270 00:09:32,679 --> 00:09:32,689 reactions again as followed we get this 271 00:09:32,689 --> 00:09:37,460 reactions again as followed we get this oxygen and two of the hydrogen here like 272 00:09:37,460 --> 00:09:37,470 oxygen and two of the hydrogen here like 273 00:09:37,470 --> 00:09:43,059 oxygen and two of the hydrogen here like this to get the water molecule out and 274 00:09:43,059 --> 00:09:43,069 this to get the water molecule out and 275 00:09:43,069 --> 00:09:56,970 this to get the water molecule out and the peptide simply linkage 276 00:09:56,970 --> 00:09:56,980 277 00:09:56,980 --> 00:10:10,750 and we have one hydrogen there like this 278 00:10:10,750 --> 00:10:10,760 and we have one hydrogen there like this 279 00:10:10,760 --> 00:10:15,880 and we have one hydrogen there like this so this is the peptide bond is this one 280 00:10:15,880 --> 00:10:15,890 so this is the peptide bond is this one 281 00:10:15,890 --> 00:10:25,810 so this is the peptide bond is this one here should probably okay this bond we 282 00:10:25,810 --> 00:10:25,820 here should probably okay this bond we 283 00:10:25,820 --> 00:10:27,820 here should probably okay this bond we bond between this carbon and that 284 00:10:27,820 --> 00:10:27,830 bond between this carbon and that 285 00:10:27,830 --> 00:10:31,230 bond between this carbon and that nitrogen is called the peptide bond 286 00:10:31,230 --> 00:10:31,240 nitrogen is called the peptide bond 287 00:10:31,240 --> 00:10:42,280 nitrogen is called the peptide bond peptide bond or peptide linkage or 288 00:10:42,280 --> 00:10:42,290 peptide bond or peptide linkage or 289 00:10:42,290 --> 00:10:46,240 peptide bond or peptide linkage or peptide bond okay so and this is 290 00:10:46,240 --> 00:10:46,250 peptide bond okay so and this is 291 00:10:46,250 --> 00:10:49,360 peptide bond okay so and this is actually called dipeptides because we 292 00:10:49,360 --> 00:10:49,370 actually called dipeptides because we 293 00:10:49,370 --> 00:10:52,480 actually called dipeptides because we have two amino acids now with the same 294 00:10:52,480 --> 00:10:52,490 have two amino acids now with the same 295 00:10:52,490 --> 00:10:55,630 have two amino acids now with the same way we can add here in other amino acids 296 00:10:55,630 --> 00:10:55,640 way we can add here in other amino acids 297 00:10:55,640 --> 00:10:57,250 way we can add here in other amino acids and other amino acids and other amino 298 00:10:57,250 --> 00:10:57,260 and other amino acids and other amino 299 00:10:57,260 --> 00:11:01,030 and other amino acids and other amino acids we get a long-chain polymer right 300 00:11:01,030 --> 00:11:01,040 acids we get a long-chain polymer right 301 00:11:01,040 --> 00:11:03,040 acids we get a long-chain polymer right and that becomes the protein that 302 00:11:03,040 --> 00:11:03,050 and that becomes the protein that 303 00:11:03,050 --> 00:11:07,300 and that becomes the protein that becomes a protein now as you can simply 304 00:11:07,300 --> 00:11:07,310 becomes a protein now as you can simply 305 00:11:07,310 --> 00:11:17,650 becomes a protein now as you can simply imagine the property of the protein will 306 00:11:17,650 --> 00:11:17,660 imagine the property of the protein will 307 00:11:17,660 --> 00:11:22,270 imagine the property of the protein will be determined which amino acids we 308 00:11:22,270 --> 00:11:22,280 be determined which amino acids we 309 00:11:22,280 --> 00:11:25,540 be determined which amino acids we condense to form the polymers and there 310 00:11:25,540 --> 00:11:25,550 condense to form the polymers and there 311 00:11:25,550 --> 00:11:28,260 condense to form the polymers and there are in fact if you consider that we have 312 00:11:28,260 --> 00:11:28,270 are in fact if you consider that we have 313 00:11:28,270 --> 00:11:33,190 are in fact if you consider that we have 22 amino acids in nature and think about 314 00:11:33,190 --> 00:11:33,200 22 amino acids in nature and think about 315 00:11:33,200 --> 00:11:38,320 22 amino acids in nature and think about that we can get up to 27 50,000 amino 316 00:11:38,320 --> 00:11:38,330 that we can get up to 27 50,000 amino 317 00:11:38,330 --> 00:11:42,100 that we can get up to 27 50,000 amino acids add them to form the peptide link 318 00:11:42,100 --> 00:11:42,110 acids add them to form the peptide link 319 00:11:42,110 --> 00:11:47,560 acids add them to form the peptide link so the sequence of those amino acids in 320 00:11:47,560 --> 00:11:47,570 so the sequence of those amino acids in 321 00:11:47,570 --> 00:11:50,680 so the sequence of those amino acids in one protein will always be limitless you 322 00:11:50,680 --> 00:11:50,690 one protein will always be limitless you 323 00:11:50,690 --> 00:11:53,680 one protein will always be limitless you can have different you can combine the 324 00:11:53,680 --> 00:11:53,690 can have different you can combine the 325 00:11:53,690 --> 00:11:56,530 can have different you can combine the same amino acids but you can have 326 00:11:56,530 --> 00:11:56,540 same amino acids but you can have 327 00:11:56,540 --> 00:11:59,350 same amino acids but you can have different proteins because the sequence 328 00:11:59,350 --> 00:11:59,360 different proteins because the sequence 329 00:11:59,360 --> 00:12:01,990 different proteins because the sequence of those amino acids will be different 330 00:12:01,990 --> 00:12:02,000 of those amino acids will be different 331 00:12:02,000 --> 00:12:04,720 of those amino acids will be different and that sequence is very very important 332 00:12:04,720 --> 00:12:04,730 and that sequence is very very important 333 00:12:04,730 --> 00:12:07,160 and that sequence is very very important in determining what function the amine 334 00:12:07,160 --> 00:12:07,170 in determining what function the amine 335 00:12:07,170 --> 00:12:10,960 in determining what function the amine the protein that is the obtain protein 336 00:12:10,960 --> 00:12:10,970 the protein that is the obtain protein 337 00:12:10,970 --> 00:12:14,000 the protein that is the obtain protein will carry out in the living organisms 338 00:12:14,000 --> 00:12:14,010 will carry out in the living organisms 339 00:12:14,010 --> 00:12:20,030 will carry out in the living organisms in the living organisms now this is 340 00:12:20,030 --> 00:12:20,040 in the living organisms now this is 341 00:12:20,040 --> 00:12:22,430 in the living organisms now this is again I just just to show you this 342 00:12:22,430 --> 00:12:22,440 again I just just to show you this 343 00:12:22,440 --> 00:12:25,639 again I just just to show you this peptide link it's the same things here 344 00:12:25,639 --> 00:12:25,649 peptide link it's the same things here 345 00:12:25,649 --> 00:12:28,449 peptide link it's the same things here right you see that peptide link between 346 00:12:28,449 --> 00:12:28,459 right you see that peptide link between 347 00:12:28,459 --> 00:12:32,420 right you see that peptide link between this carbon and that nitrogen over here 348 00:12:32,420 --> 00:12:32,430 this carbon and that nitrogen over here 349 00:12:32,430 --> 00:12:34,460 this carbon and that nitrogen over here and now we have another peptide link 350 00:12:34,460 --> 00:12:34,470 and now we have another peptide link 351 00:12:34,470 --> 00:12:37,040 and now we have another peptide link that carbon there this is a tripeptide 352 00:12:37,040 --> 00:12:37,050 that carbon there this is a tripeptide 353 00:12:37,050 --> 00:12:40,759 that carbon there this is a tripeptide we have three amino acids remember we 354 00:12:40,759 --> 00:12:40,769 we have three amino acids remember we 355 00:12:40,769 --> 00:12:45,769 we have three amino acids remember we can have 30 to 50 amino acids or more in 356 00:12:45,769 --> 00:12:45,779 can have 30 to 50 amino acids or more in 357 00:12:45,779 --> 00:12:49,250 can have 30 to 50 amino acids or more in one chain protein that gives you the big 358 00:12:49,250 --> 00:12:49,260 one chain protein that gives you the big 359 00:12:49,260 --> 00:12:52,819 one chain protein that gives you the big big molecular weight of proteins let's 360 00:12:52,819 --> 00:12:52,829 big molecular weight of proteins let's 361 00:12:52,829 --> 00:12:56,360 big molecular weight of proteins let's continue now the protein structures are 362 00:12:56,360 --> 00:12:56,370 continue now the protein structures are 363 00:12:56,370 --> 00:12:59,350 continue now the protein structures are also classified as primary structure of 364 00:12:59,350 --> 00:12:59,360 also classified as primary structure of 365 00:12:59,360 --> 00:13:02,269 also classified as primary structure of proteins it is called the sequence of 366 00:13:02,269 --> 00:13:02,279 proteins it is called the sequence of 367 00:13:02,279 --> 00:13:05,210 proteins it is called the sequence of amino acids in the polypeptide protein 368 00:13:05,210 --> 00:13:05,220 amino acids in the polypeptide protein 369 00:13:05,220 --> 00:13:07,519 amino acids in the polypeptide protein chain what does that means that means 370 00:13:07,519 --> 00:13:07,529 chain what does that means that means 371 00:13:07,529 --> 00:13:10,579 chain what does that means that means which amino acids that we will simply 372 00:13:10,579 --> 00:13:10,589 which amino acids that we will simply 373 00:13:10,589 --> 00:13:12,410 which amino acids that we will simply bring together this is like glycine 374 00:13:12,410 --> 00:13:12,420 bring together this is like glycine 375 00:13:12,420 --> 00:13:15,530 bring together this is like glycine alanine and other amino acids that 376 00:13:15,530 --> 00:13:15,540 alanine and other amino acids that 377 00:13:15,540 --> 00:13:18,650 alanine and other amino acids that sequence it determines the primary 378 00:13:18,650 --> 00:13:18,660 sequence it determines the primary 379 00:13:18,660 --> 00:13:21,170 sequence it determines the primary structure of the amino acids now the 380 00:13:21,170 --> 00:13:21,180 structure of the amino acids now the 381 00:13:21,180 --> 00:13:23,720 structure of the amino acids now the secretary structure is the interactions 382 00:13:23,720 --> 00:13:23,730 secretary structure is the interactions 383 00:13:23,730 --> 00:13:26,630 secretary structure is the interactions between the chain atoms in fact carbon 384 00:13:26,630 --> 00:13:26,640 between the chain atoms in fact carbon 385 00:13:26,640 --> 00:13:29,329 between the chain atoms in fact carbon double bond oxygen this carbonyl and NH 386 00:13:29,329 --> 00:13:29,339 double bond oxygen this carbonyl and NH 387 00:13:29,339 --> 00:13:31,939 double bond oxygen this carbonyl and NH atoms remember we will have a hydrogen 388 00:13:31,939 --> 00:13:31,949 atoms remember we will have a hydrogen 389 00:13:31,949 --> 00:13:34,250 atoms remember we will have a hydrogen bond between that hydrogen and that 390 00:13:34,250 --> 00:13:34,260 bond between that hydrogen and that 391 00:13:34,260 --> 00:13:36,350 bond between that hydrogen and that oxygen electron pairs on that oxygen 392 00:13:36,350 --> 00:13:36,360 oxygen electron pairs on that oxygen 393 00:13:36,360 --> 00:13:39,230 oxygen electron pairs on that oxygen right lone pair electrons so that gives 394 00:13:39,230 --> 00:13:39,240 right lone pair electrons so that gives 395 00:13:39,240 --> 00:13:41,410 right lone pair electrons so that gives this structure two proteins that 396 00:13:41,410 --> 00:13:41,420 this structure two proteins that 397 00:13:41,420 --> 00:13:43,280 this structure two proteins that interaction is the hydrogen bond 398 00:13:43,280 --> 00:13:43,290 interaction is the hydrogen bond 399 00:13:43,290 --> 00:13:46,189 interaction is the hydrogen bond interactions is a very very important 400 00:13:46,189 --> 00:13:46,199 interactions is a very very important 401 00:13:46,199 --> 00:13:48,920 interactions is a very very important factor in determining the structure of 402 00:13:48,920 --> 00:13:48,930 factor in determining the structure of 403 00:13:48,930 --> 00:13:50,870 factor in determining the structure of the particularly at secondary structure 404 00:13:50,870 --> 00:13:50,880 the particularly at secondary structure 405 00:13:50,880 --> 00:13:53,030 the particularly at secondary structure of the proteins as we will see now 406 00:13:53,030 --> 00:13:53,040 of the proteins as we will see now 407 00:13:53,040 --> 00:13:55,400 of the proteins as we will see now tertiary structures are intermolecular 408 00:13:55,400 --> 00:13:55,410 tertiary structures are intermolecular 409 00:13:55,410 --> 00:13:58,009 tertiary structures are intermolecular forces between the sidechain atoms that 410 00:13:58,009 --> 00:13:58,019 forces between the sidechain atoms that 411 00:13:58,019 --> 00:14:00,560 forces between the sidechain atoms that gives structure to proteins this is 412 00:14:00,560 --> 00:14:00,570 gives structure to proteins this is 413 00:14:00,570 --> 00:14:03,199 gives structure to proteins this is simply the folding actually you know 414 00:14:03,199 --> 00:14:03,209 simply the folding actually you know 415 00:14:03,209 --> 00:14:06,430 simply the folding actually you know when you have a long long chain of 416 00:14:06,430 --> 00:14:06,440 when you have a long long chain of 417 00:14:06,440 --> 00:14:10,790 when you have a long long chain of protein molecule now it simply folds up 418 00:14:10,790 --> 00:14:10,800 protein molecule now it simply folds up 419 00:14:10,800 --> 00:14:14,689 protein molecule now it simply folds up and the folding of the assembling of 420 00:14:14,689 --> 00:14:14,699 and the folding of the assembling of 421 00:14:14,699 --> 00:14:17,449 and the folding of the assembling of that long chain folding is very very 422 00:14:17,449 --> 00:14:17,459 that long chain folding is very very 423 00:14:17,459 --> 00:14:19,370 that long chain folding is very very important because the folding of the 424 00:14:19,370 --> 00:14:19,380 important because the folding of the 425 00:14:19,380 --> 00:14:20,990 important because the folding of the amino acids 426 00:14:20,990 --> 00:14:21,000 amino acids 427 00:14:21,000 --> 00:14:23,480 amino acids the shape of the amino acid determines 428 00:14:23,480 --> 00:14:23,490 the shape of the amino acid determines 429 00:14:23,490 --> 00:14:25,340 the shape of the amino acid determines the protein the folding of the amino 430 00:14:25,340 --> 00:14:25,350 the protein the folding of the amino 431 00:14:25,350 --> 00:14:27,530 the protein the folding of the amino acids in the protein determines the 432 00:14:27,530 --> 00:14:27,540 acids in the protein determines the 433 00:14:27,540 --> 00:14:29,960 acids in the protein determines the shape of the protein and the shape of 434 00:14:29,960 --> 00:14:29,970 shape of the protein and the shape of 435 00:14:29,970 --> 00:14:33,410 shape of the protein and the shape of the protein also determines the function 436 00:14:33,410 --> 00:14:33,420 the protein also determines the function 437 00:14:33,420 --> 00:14:36,290 the protein also determines the function of the chemical functions of the protein 438 00:14:36,290 --> 00:14:36,300 of the chemical functions of the protein 439 00:14:36,300 --> 00:14:38,480 of the chemical functions of the protein that will carry will carry out in the 440 00:14:38,480 --> 00:14:38,490 that will carry will carry out in the 441 00:14:38,490 --> 00:14:41,030 that will carry will carry out in the living organisms we will see this now 442 00:14:41,030 --> 00:14:41,040 living organisms we will see this now 443 00:14:41,040 --> 00:14:44,990 living organisms we will see this now the quaternary structures is another in 444 00:14:44,990 --> 00:14:45,000 the quaternary structures is another in 445 00:14:45,000 --> 00:14:48,860 the quaternary structures is another in one protein we may have units subunits 446 00:14:48,860 --> 00:14:48,870 one protein we may have units subunits 447 00:14:48,870 --> 00:14:50,720 one protein we may have units subunits and again the assembling of those 448 00:14:50,720 --> 00:14:50,730 and again the assembling of those 449 00:14:50,730 --> 00:14:52,760 and again the assembling of those subunits arrangement of those multiple 450 00:14:52,760 --> 00:14:52,770 subunits arrangement of those multiple 451 00:14:52,770 --> 00:14:55,610 subunits arrangement of those multiple units incorporated in non amino acid 452 00:14:55,610 --> 00:14:55,620 units incorporated in non amino acid 453 00:14:55,620 --> 00:15:00,500 units incorporated in non amino acid proteins of proteins it gives you the 454 00:15:00,500 --> 00:15:00,510 proteins of proteins it gives you the 455 00:15:00,510 --> 00:15:03,410 proteins of proteins it gives you the quaternary structures again let's see 456 00:15:03,410 --> 00:15:03,420 quaternary structures again let's see 457 00:15:03,420 --> 00:15:06,800 quaternary structures again let's see what we mean by this this is again the 458 00:15:06,800 --> 00:15:06,810 what we mean by this this is again the 459 00:15:06,810 --> 00:15:09,470 what we mean by this this is again the the structures of the protein this is 460 00:15:09,470 --> 00:15:09,480 the structures of the protein this is 461 00:15:09,480 --> 00:15:12,920 the structures of the protein this is the primary structure right that means 462 00:15:12,920 --> 00:15:12,930 the primary structure right that means 463 00:15:12,930 --> 00:15:16,040 the primary structure right that means the sequence of the amino acids which 464 00:15:16,040 --> 00:15:16,050 the sequence of the amino acids which 465 00:15:16,050 --> 00:15:18,230 the sequence of the amino acids which amino acids are linked together by 466 00:15:18,230 --> 00:15:18,240 amino acids are linked together by 467 00:15:18,240 --> 00:15:20,900 amino acids are linked together by peptide link and in this chain that's 468 00:15:20,900 --> 00:15:20,910 peptide link and in this chain that's 469 00:15:20,910 --> 00:15:24,590 peptide link and in this chain that's the primary structure now the secondary 470 00:15:24,590 --> 00:15:24,600 the primary structure now the secondary 471 00:15:24,600 --> 00:15:27,470 the primary structure now the secondary structure we may simply have the helix 472 00:15:27,470 --> 00:15:27,480 structure we may simply have the helix 473 00:15:27,480 --> 00:15:30,770 structure we may simply have the helix type structure like this or we may have 474 00:15:30,770 --> 00:15:30,780 type structure like this or we may have 475 00:15:30,780 --> 00:15:33,050 type structure like this or we may have a planar structure like this again 476 00:15:33,050 --> 00:15:33,060 a planar structure like this again 477 00:15:33,060 --> 00:15:36,650 a planar structure like this again remember all of these structures we have 478 00:15:36,650 --> 00:15:36,660 remember all of these structures we have 479 00:15:36,660 --> 00:15:40,690 remember all of these structures we have a very strong interactions between the 480 00:15:40,690 --> 00:15:40,700 a very strong interactions between the 481 00:15:40,700 --> 00:15:43,760 a very strong interactions between the nitrogen and the oxygen groups again and 482 00:15:43,760 --> 00:15:43,770 nitrogen and the oxygen groups again and 483 00:15:43,770 --> 00:15:46,760 nitrogen and the oxygen groups again and particularly the form in the helix 484 00:15:46,760 --> 00:15:46,770 particularly the form in the helix 485 00:15:46,770 --> 00:15:49,970 particularly the form in the helix structure that allows the interactions 486 00:15:49,970 --> 00:15:49,980 structure that allows the interactions 487 00:15:49,980 --> 00:15:52,490 structure that allows the interactions the hydrogen bonding between the strain 488 00:15:52,490 --> 00:15:52,500 the hydrogen bonding between the strain 489 00:15:52,500 --> 00:15:56,260 the hydrogen bonding between the strain of the protein strain of the protein and 490 00:15:56,260 --> 00:15:56,270 of the protein strain of the protein and 491 00:15:56,270 --> 00:15:59,329 of the protein strain of the protein and this is called the beta sheet it's sort 492 00:15:59,329 --> 00:15:59,339 this is called the beta sheet it's sort 493 00:15:59,339 --> 00:16:02,390 this is called the beta sheet it's sort of a planar structures like this now 494 00:16:02,390 --> 00:16:02,400 of a planar structures like this now 495 00:16:02,400 --> 00:16:05,030 of a planar structures like this now when you have those and fold them up 496 00:16:05,030 --> 00:16:05,040 when you have those and fold them up 497 00:16:05,040 --> 00:16:06,440 when you have those and fold them up here like this 498 00:16:06,440 --> 00:16:06,450 here like this 499 00:16:06,450 --> 00:16:08,780 here like this that becomes the tertiary structures now 500 00:16:08,780 --> 00:16:08,790 that becomes the tertiary structures now 501 00:16:08,790 --> 00:16:12,079 that becomes the tertiary structures now if you have a bigger protein which have 502 00:16:12,079 --> 00:16:12,089 if you have a bigger protein which have 503 00:16:12,089 --> 00:16:14,750 if you have a bigger protein which have subunits and have this kind of structure 504 00:16:14,750 --> 00:16:14,760 subunits and have this kind of structure 505 00:16:14,760 --> 00:16:17,090 subunits and have this kind of structure again every subunit has different 506 00:16:17,090 --> 00:16:17,100 again every subunit has different 507 00:16:17,100 --> 00:16:19,930 again every subunit has different structure this different assembling 508 00:16:19,930 --> 00:16:19,940 structure this different assembling 509 00:16:19,940 --> 00:16:23,530 structure this different assembling structures and that gives you the 510 00:16:23,530 --> 00:16:23,540 structures and that gives you the 511 00:16:23,540 --> 00:16:29,240 structures and that gives you the quaternary structures of the protein now 512 00:16:29,240 --> 00:16:29,250 quaternary structures of the protein now 513 00:16:29,250 --> 00:16:31,760 quaternary structures of the protein now the primary structure formations of the 514 00:16:31,760 --> 00:16:31,770 the primary structure formations of the 515 00:16:31,770 --> 00:16:34,360 the primary structure formations of the mi band between amino acid 516 00:16:34,360 --> 00:16:34,370 mi band between amino acid 517 00:16:34,370 --> 00:16:37,449 mi band between amino acid repeats many times for polypeptide 518 00:16:37,449 --> 00:16:37,459 repeats many times for polypeptide 519 00:16:37,459 --> 00:16:40,269 repeats many times for polypeptide protein again to get that million 520 00:16:40,269 --> 00:16:40,279 protein again to get that million 521 00:16:40,279 --> 00:16:43,840 protein again to get that million molecular mass atomic mass unit for the 522 00:16:43,840 --> 00:16:43,850 molecular mass atomic mass unit for the 523 00:16:43,850 --> 00:16:45,939 molecular mass atomic mass unit for the proteins it's a very very large long 524 00:16:45,939 --> 00:16:45,949 proteins it's a very very large long 525 00:16:45,949 --> 00:16:48,730 proteins it's a very very large long chain here is the glycine and alanine 526 00:16:48,730 --> 00:16:48,740 chain here is the glycine and alanine 527 00:16:48,740 --> 00:16:54,309 chain here is the glycine and alanine and we get the glycine alanine protein 528 00:16:54,309 --> 00:16:54,319 and we get the glycine alanine protein 529 00:16:54,319 --> 00:16:56,920 and we get the glycine alanine protein and that we will add more and more of 530 00:16:56,920 --> 00:16:56,930 and that we will add more and more of 531 00:16:56,930 --> 00:17:00,400 and that we will add more and more of that now the secondary structure as we 532 00:17:00,400 --> 00:17:00,410 that now the secondary structure as we 533 00:17:00,410 --> 00:17:02,319 that now the secondary structure as we talked about that two common times it 534 00:17:02,319 --> 00:17:02,329 talked about that two common times it 535 00:17:02,329 --> 00:17:04,960 talked about that two common times it says alpha helix as I showed you looks 536 00:17:04,960 --> 00:17:04,970 says alpha helix as I showed you looks 537 00:17:04,970 --> 00:17:08,980 says alpha helix as I showed you looks like a corkscrew or spiral staircases 538 00:17:08,980 --> 00:17:08,990 like a corkscrew or spiral staircases 539 00:17:08,990 --> 00:17:12,490 like a corkscrew or spiral staircases the carbon oxygen forms hydrogen bonds 540 00:17:12,490 --> 00:17:12,500 the carbon oxygen forms hydrogen bonds 541 00:17:12,500 --> 00:17:15,210 the carbon oxygen forms hydrogen bonds with the nitrogen hydrogen from the 542 00:17:15,210 --> 00:17:15,220 with the nitrogen hydrogen from the 543 00:17:15,220 --> 00:17:19,419 with the nitrogen hydrogen from the another amino acid in the chain right so 544 00:17:19,419 --> 00:17:19,429 another amino acid in the chain right so 545 00:17:19,429 --> 00:17:23,350 another amino acid in the chain right so another strain of the amino acids now 546 00:17:23,350 --> 00:17:23,360 another strain of the amino acids now 547 00:17:23,360 --> 00:17:26,350 another strain of the amino acids now better sheet two or more pleated regions 548 00:17:26,350 --> 00:17:26,360 better sheet two or more pleated regions 549 00:17:26,360 --> 00:17:28,539 better sheet two or more pleated regions looking like a shape of the pleated 550 00:17:28,539 --> 00:17:28,549 looking like a shape of the pleated 551 00:17:28,549 --> 00:17:31,960 looking like a shape of the pleated skirt or corrugated cardboard are held 552 00:17:31,960 --> 00:17:31,970 skirt or corrugated cardboard are held 553 00:17:31,970 --> 00:17:34,360 skirt or corrugated cardboard are held together by the same hydrogen bonds as 554 00:17:34,360 --> 00:17:34,370 together by the same hydrogen bonds as 555 00:17:34,370 --> 00:17:37,630 together by the same hydrogen bonds as an alpha helix one major difference is 556 00:17:37,630 --> 00:17:37,640 an alpha helix one major difference is 557 00:17:37,640 --> 00:17:40,000 an alpha helix one major difference is how far apart from each other the amino 558 00:17:40,000 --> 00:17:40,010 how far apart from each other the amino 559 00:17:40,010 --> 00:17:43,029 how far apart from each other the amino acids are in the amino acid sequence of 560 00:17:43,029 --> 00:17:43,039 acids are in the amino acid sequence of 561 00:17:43,039 --> 00:17:45,250 acids are in the amino acid sequence of alpha helix atoms are much closer 562 00:17:45,250 --> 00:17:45,260 alpha helix atoms are much closer 563 00:17:45,260 --> 00:17:48,100 alpha helix atoms are much closer together in alpha helix the hydrogen 564 00:17:48,100 --> 00:17:48,110 together in alpha helix the hydrogen 565 00:17:48,110 --> 00:17:49,870 together in alpha helix the hydrogen bundles are taking place in much closer 566 00:17:49,870 --> 00:17:49,880 bundles are taking place in much closer 567 00:17:49,880 --> 00:17:52,720 bundles are taking place in much closer distances in beta the beta sheet 568 00:17:52,720 --> 00:17:52,730 distances in beta the beta sheet 569 00:17:52,730 --> 00:17:57,750 distances in beta the beta sheet structure again it is longer distance 570 00:17:57,750 --> 00:17:57,760 structure again it is longer distance 571 00:17:57,760 --> 00:18:01,000 structure again it is longer distance hydrogen bonded now tertiary structures 572 00:18:01,000 --> 00:18:01,010 hydrogen bonded now tertiary structures 573 00:18:01,010 --> 00:18:03,669 hydrogen bonded now tertiary structures side chains interact with each other and 574 00:18:03,669 --> 00:18:03,679 side chains interact with each other and 575 00:18:03,679 --> 00:18:05,639 side chains interact with each other and the surrounding environment usually 576 00:18:05,639 --> 00:18:05,649 the surrounding environment usually 577 00:18:05,649 --> 00:18:09,100 the surrounding environment usually aqueous environment the forces we called 578 00:18:09,100 --> 00:18:09,110 aqueous environment the forces we called 579 00:18:09,110 --> 00:18:11,799 aqueous environment the forces we called intermolecular are mostly what drives 580 00:18:11,799 --> 00:18:11,809 intermolecular are mostly what drives 581 00:18:11,809 --> 00:18:13,750 intermolecular are mostly what drives the tertiary structures we have the 582 00:18:13,750 --> 00:18:13,760 the tertiary structures we have the 583 00:18:13,760 --> 00:18:16,240 the tertiary structures we have the intermolecular forces and the side 584 00:18:16,240 --> 00:18:16,250 intermolecular forces and the side 585 00:18:16,250 --> 00:18:18,789 intermolecular forces and the side chains have polar nonpolar and charged 586 00:18:18,789 --> 00:18:18,799 chains have polar nonpolar and charged 587 00:18:18,799 --> 00:18:21,760 chains have polar nonpolar and charged groups these give rise to ion ion ion 588 00:18:21,760 --> 00:18:21,770 groups these give rise to ion ion ion 589 00:18:21,770 --> 00:18:24,580 groups these give rise to ion ion ion dipole dipole dipole and dispersion 590 00:18:24,580 --> 00:18:24,590 dipole dipole dipole and dispersion 591 00:18:24,590 --> 00:18:26,980 dipole dipole dipole and dispersion force interactions and definitely 592 00:18:26,980 --> 00:18:26,990 force interactions and definitely 593 00:18:26,990 --> 00:18:28,750 force interactions and definitely hydrogen bonds and hydrogen bonds is 594 00:18:28,750 --> 00:18:28,760 hydrogen bonds and hydrogen bonds is 595 00:18:28,760 --> 00:18:33,430 hydrogen bonds and hydrogen bonds is definitely there too now the quaternary 596 00:18:33,430 --> 00:18:33,440 definitely there too now the quaternary 597 00:18:33,440 --> 00:18:36,430 definitely there too now the quaternary structures some proteins are made up of 598 00:18:36,430 --> 00:18:36,440 structures some proteins are made up of 599 00:18:36,440 --> 00:18:39,460 structures some proteins are made up of more than one polypeptide chain more 600 00:18:39,460 --> 00:18:39,470 more than one polypeptide chain more 601 00:18:39,470 --> 00:18:42,250 more than one polypeptide chain more than one that means subunits some 602 00:18:42,250 --> 00:18:42,260 than one that means subunits some 603 00:18:42,260 --> 00:18:45,010 than one that means subunits some proteins contain portions that are not 604 00:18:45,010 --> 00:18:45,020 proteins contain portions that are not 605 00:18:45,020 --> 00:18:47,680 proteins contain portions that are not amino acids in the nature and the 606 00:18:47,680 --> 00:18:47,690 amino acids in the nature and the 607 00:18:47,690 --> 00:18:49,509 amino acids in the nature and the combinations of subunits all these 608 00:18:49,509 --> 00:18:49,519 combinations of subunits all these 609 00:18:49,519 --> 00:18:52,810 combinations of subunits all these subunits is quaternary structures when 610 00:18:52,810 --> 00:18:52,820 subunits is quaternary structures when 611 00:18:52,820 --> 00:18:55,060 subunits is quaternary structures when they get together form a shape that's 612 00:18:55,060 --> 00:18:55,070 they get together form a shape that's 613 00:18:55,070 --> 00:18:58,499 they get together form a shape that's the this fourth structure of the 614 00:18:58,499 --> 00:18:58,509 the this fourth structure of the 615 00:18:58,509 --> 00:19:03,519 the this fourth structure of the proteins now this gives you another 616 00:19:03,519 --> 00:19:03,529 proteins now this gives you another 617 00:19:03,529 --> 00:19:06,549 proteins now this gives you another classifications of proteins says one 618 00:19:06,549 --> 00:19:06,559 classifications of proteins says one 619 00:19:06,559 --> 00:19:09,090 classifications of proteins says one method to classify proteins is based on 620 00:19:09,090 --> 00:19:09,100 method to classify proteins is based on 621 00:19:09,100 --> 00:19:12,490 method to classify proteins is based on solubility global proteins are roughly 622 00:19:12,490 --> 00:19:12,500 solubility global proteins are roughly 623 00:19:12,500 --> 00:19:15,009 solubility global proteins are roughly spherical and dissolve in aqueous 624 00:19:15,009 --> 00:19:15,019 spherical and dissolve in aqueous 625 00:19:15,019 --> 00:19:17,350 spherical and dissolve in aqueous environment this is the globular that 626 00:19:17,350 --> 00:19:17,360 environment this is the globular that 627 00:19:17,360 --> 00:19:20,409 environment this is the globular that means spherical type and fibrous 628 00:19:20,409 --> 00:19:20,419 means spherical type and fibrous 629 00:19:20,419 --> 00:19:24,879 means spherical type and fibrous proteins long-chain are usually long 630 00:19:24,879 --> 00:19:24,889 proteins long-chain are usually long 631 00:19:24,889 --> 00:19:27,310 proteins long-chain are usually long fibers that are insoluble in water and 632 00:19:27,310 --> 00:19:27,320 fibers that are insoluble in water and 633 00:19:27,320 --> 00:19:30,669 fibers that are insoluble in water and are used as structural materials as 634 00:19:30,669 --> 00:19:30,679 are used as structural materials as 635 00:19:30,679 --> 00:19:33,279 are used as structural materials as structural materials that means in the 636 00:19:33,279 --> 00:19:33,289 structural materials that means in the 637 00:19:33,289 --> 00:19:35,740 structural materials that means in the living organisms like skins and muscles 638 00:19:35,740 --> 00:19:35,750 living organisms like skins and muscles 639 00:19:35,750 --> 00:19:39,299 living organisms like skins and muscles and things like that as a matter of fact 640 00:19:39,299 --> 00:19:39,309 and things like that as a matter of fact 641 00:19:39,309 --> 00:19:44,580 and things like that as a matter of fact now the second biopolymers is 642 00:19:44,580 --> 00:19:44,590 now the second biopolymers is 643 00:19:44,590 --> 00:19:48,369 now the second biopolymers is carbohydrates now the name comes from 644 00:19:48,369 --> 00:19:48,379 carbohydrates now the name comes from 645 00:19:48,379 --> 00:19:52,210 carbohydrates now the name comes from the empirical formula for sugars which 646 00:19:52,210 --> 00:19:52,220 the empirical formula for sugars which 647 00:19:52,220 --> 00:19:54,970 the empirical formula for sugars which has this empirical formula for the 648 00:19:54,970 --> 00:19:54,980 has this empirical formula for the 649 00:19:54,980 --> 00:19:57,310 has this empirical formula for the simplest sugars X is equal to Y which is 650 00:19:57,310 --> 00:19:57,320 simplest sugars X is equal to Y which is 651 00:19:57,320 --> 00:20:00,279 simplest sugars X is equal to Y which is the glucose as we will see it now what 652 00:20:00,279 --> 00:20:00,289 the glucose as we will see it now what 653 00:20:00,289 --> 00:20:02,560 the glucose as we will see it now what does this mean this means like we have X 654 00:20:02,560 --> 00:20:02,570 does this mean this means like we have X 655 00:20:02,570 --> 00:20:04,960 does this mean this means like we have X carbon atoms and like we have this 656 00:20:04,960 --> 00:20:04,970 carbon atoms and like we have this 657 00:20:04,970 --> 00:20:06,999 carbon atoms and like we have this carbon atom is hydrated with water 658 00:20:06,999 --> 00:20:07,009 carbon atom is hydrated with water 659 00:20:07,009 --> 00:20:10,450 carbon atom is hydrated with water molecules hydration is simply means the 660 00:20:10,450 --> 00:20:10,460 molecules hydration is simply means the 661 00:20:10,460 --> 00:20:14,710 molecules hydration is simply means the surround the atoms or the molecule with 662 00:20:14,710 --> 00:20:14,720 surround the atoms or the molecule with 663 00:20:14,720 --> 00:20:20,129 surround the atoms or the molecule with water molecules but in reality the 664 00:20:20,129 --> 00:20:20,139 water molecules but in reality the 665 00:20:20,139 --> 00:20:22,570 water molecules but in reality the carbohydrates they are not actually 666 00:20:22,570 --> 00:20:22,580 carbohydrates they are not actually 667 00:20:22,580 --> 00:20:25,389 carbohydrates they are not actually carbohydrates they are simply compounds 668 00:20:25,389 --> 00:20:25,399 carbohydrates they are simply compounds 669 00:20:25,399 --> 00:20:27,669 carbohydrates they are simply compounds of carbon hydrogen or oxygen that's it 670 00:20:27,669 --> 00:20:27,679 of carbon hydrogen or oxygen that's it 671 00:20:27,679 --> 00:20:28,570 of carbon hydrogen or oxygen that's it right 672 00:20:28,570 --> 00:20:28,580 right 673 00:20:28,580 --> 00:20:32,230 right but the ratio of the hydrogen and oxygen 674 00:20:32,230 --> 00:20:32,240 but the ratio of the hydrogen and oxygen 675 00:20:32,240 --> 00:20:35,409 but the ratio of the hydrogen and oxygen always wanted to so that means we can 676 00:20:35,409 --> 00:20:35,419 always wanted to so that means we can 677 00:20:35,419 --> 00:20:39,369 always wanted to so that means we can always write the formula as this certain 678 00:20:39,369 --> 00:20:39,379 always write the formula as this certain 679 00:20:39,379 --> 00:20:41,019 always write the formula as this certain number of carbon atoms and certain 680 00:20:41,019 --> 00:20:41,029 number of carbon atoms and certain 681 00:20:41,029 --> 00:20:42,789 number of carbon atoms and certain number of water molecules that's what we 682 00:20:42,789 --> 00:20:42,799 number of water molecules that's what we 683 00:20:42,799 --> 00:20:45,789 number of water molecules that's what we call it high grade carbohydrates like 684 00:20:45,789 --> 00:20:45,799 call it high grade carbohydrates like 685 00:20:45,799 --> 00:20:49,330 call it high grade carbohydrates like hydrated carbon hydrated carbon but in 686 00:20:49,330 --> 00:20:49,340 hydrated carbon hydrated carbon but in 687 00:20:49,340 --> 00:20:51,399 hydrated carbon hydrated carbon but in reality it is not actually we have to 688 00:20:51,399 --> 00:20:51,409 reality it is not actually we have to 689 00:20:51,409 --> 00:20:54,850 reality it is not actually we have to remember that now simple sugar which is 690 00:20:54,850 --> 00:20:54,860 remember that now simple sugar which is 691 00:20:54,860 --> 00:20:57,999 remember that now simple sugar which is the monosaccharides are poly hydroxy 692 00:20:57,999 --> 00:20:58,009 the monosaccharides are poly hydroxy 693 00:20:58,009 --> 00:21:01,330 the monosaccharides are poly hydroxy aldehyde or ketone 694 00:21:01,330 --> 00:21:01,340 695 00:21:01,340 --> 00:21:04,960 again this is what the plant synthesizes 696 00:21:04,960 --> 00:21:04,970 again this is what the plant synthesizes 697 00:21:04,970 --> 00:21:07,720 again this is what the plant synthesizes in photosynthesis right in 698 00:21:07,720 --> 00:21:07,730 in photosynthesis right in 699 00:21:07,730 --> 00:21:10,539 in photosynthesis right in photosynthesis they are often drawn as 700 00:21:10,539 --> 00:21:10,549 photosynthesis they are often drawn as 701 00:21:10,549 --> 00:21:13,269 photosynthesis they are often drawn as chains but most frequently exists as 702 00:21:13,269 --> 00:21:13,279 chains but most frequently exists as 703 00:21:13,279 --> 00:21:17,110 chains but most frequently exists as rings in solutions so for example 704 00:21:17,110 --> 00:21:17,120 rings in solutions so for example 705 00:21:17,120 --> 00:21:19,659 rings in solutions so for example glucose this is the alpha glucose beta 706 00:21:19,659 --> 00:21:19,669 glucose this is the alpha glucose beta 707 00:21:19,669 --> 00:21:21,310 glucose this is the alpha glucose beta glucose what is the difference the 708 00:21:21,310 --> 00:21:21,320 glucose what is the difference the 709 00:21:21,320 --> 00:21:23,529 glucose what is the difference the difference actually is the positions of 710 00:21:23,529 --> 00:21:23,539 difference actually is the positions of 711 00:21:23,539 --> 00:21:25,600 difference actually is the positions of this Oh H with respect to this group 712 00:21:25,600 --> 00:21:25,610 this Oh H with respect to this group 713 00:21:25,610 --> 00:21:28,210 this Oh H with respect to this group over here these are in the same side and 714 00:21:28,210 --> 00:21:28,220 over here these are in the same side and 715 00:21:28,220 --> 00:21:30,519 over here these are in the same side and over here this on this side that on that 716 00:21:30,519 --> 00:21:30,529 over here this on this side that on that 717 00:21:30,529 --> 00:21:32,289 over here this on this side that on that side that's the alpha this is the beta 718 00:21:32,289 --> 00:21:32,299 side that's the alpha this is the beta 719 00:21:32,299 --> 00:21:35,919 side that's the alpha this is the beta glucose actually six carbon and then we 720 00:21:35,919 --> 00:21:35,929 glucose actually six carbon and then we 721 00:21:35,929 --> 00:21:39,159 glucose actually six carbon and then we have six oxygen and 12 hydrogen right 722 00:21:39,159 --> 00:21:39,169 have six oxygen and 12 hydrogen right 723 00:21:39,169 --> 00:21:42,549 have six oxygen and 12 hydrogen right and it is an aldehyde it is an aldehyde 724 00:21:42,549 --> 00:21:42,559 and it is an aldehyde it is an aldehyde 725 00:21:42,559 --> 00:21:46,840 and it is an aldehyde it is an aldehyde and also ketones as we say now here you 726 00:21:46,840 --> 00:21:46,850 and also ketones as we say now here you 727 00:21:46,850 --> 00:21:50,230 and also ketones as we say now here you will see those this is the glucose six 728 00:21:50,230 --> 00:21:50,240 will see those this is the glucose six 729 00:21:50,240 --> 00:21:53,499 will see those this is the glucose six carbon and it is an aldehyde you see 730 00:21:53,499 --> 00:21:53,509 carbon and it is an aldehyde you see 731 00:21:53,509 --> 00:21:55,029 carbon and it is an aldehyde you see again we have a double bond and the 732 00:21:55,029 --> 00:21:55,039 again we have a double bond and the 733 00:21:55,039 --> 00:21:57,100 again we have a double bond and the hydrogen at the end this is the aldehyde 734 00:21:57,100 --> 00:21:57,110 hydrogen at the end this is the aldehyde 735 00:21:57,110 --> 00:22:00,730 hydrogen at the end this is the aldehyde and it also has a H group that means it 736 00:22:00,730 --> 00:22:00,740 and it also has a H group that means it 737 00:22:00,740 --> 00:22:03,940 and it also has a H group that means it is actually a alcohol it is a poly 738 00:22:03,940 --> 00:22:03,950 is actually a alcohol it is a poly 739 00:22:03,950 --> 00:22:09,100 is actually a alcohol it is a poly hydroxyl aldehyde poly hydroxyl aldehyde 740 00:22:09,100 --> 00:22:09,110 hydroxyl aldehyde poly hydroxyl aldehyde 741 00:22:09,110 --> 00:22:13,330 hydroxyl aldehyde poly hydroxyl aldehyde now this is the fructose which is 742 00:22:13,330 --> 00:22:13,340 now this is the fructose which is 743 00:22:13,340 --> 00:22:16,180 now this is the fructose which is present in fruits particularly and it is 744 00:22:16,180 --> 00:22:16,190 present in fruits particularly and it is 745 00:22:16,190 --> 00:22:19,240 present in fruits particularly and it is also six carbon and the close formula is 746 00:22:19,240 --> 00:22:19,250 also six carbon and the close formula is 747 00:22:19,250 --> 00:22:21,879 also six carbon and the close formula is exactly the same but this is a ketone 748 00:22:21,879 --> 00:22:21,889 exactly the same but this is a ketone 749 00:22:21,889 --> 00:22:24,369 exactly the same but this is a ketone you see again the ketone there and again 750 00:22:24,369 --> 00:22:24,379 you see again the ketone there and again 751 00:22:24,379 --> 00:22:27,220 you see again the ketone there and again we have the hydroxide group now remember 752 00:22:27,220 --> 00:22:27,230 we have the hydroxide group now remember 753 00:22:27,230 --> 00:22:29,970 we have the hydroxide group now remember these are the monomers of 754 00:22:29,970 --> 00:22:29,980 these are the monomers of 755 00:22:29,980 --> 00:22:33,060 these are the monomers of polysaccharides right polysaccharides 756 00:22:33,060 --> 00:22:33,070 polysaccharides right polysaccharides 757 00:22:33,070 --> 00:22:37,710 polysaccharides right polysaccharides again carbohydrates or both yay now 758 00:22:37,710 --> 00:22:37,720 again carbohydrates or both yay now 759 00:22:37,720 --> 00:22:41,049 again carbohydrates or both yay now disaccharide is simply obtained by 760 00:22:41,049 --> 00:22:41,059 disaccharide is simply obtained by 761 00:22:41,059 --> 00:22:44,019 disaccharide is simply obtained by combining two of these glucose or 762 00:22:44,019 --> 00:22:44,029 combining two of these glucose or 763 00:22:44,029 --> 00:22:47,440 combining two of these glucose or fructose units together and when you 764 00:22:47,440 --> 00:22:47,450 fructose units together and when you 765 00:22:47,450 --> 00:22:50,649 fructose units together and when you combine these two units like glucose and 766 00:22:50,649 --> 00:22:50,659 combine these two units like glucose and 767 00:22:50,659 --> 00:22:53,610 combine these two units like glucose and fructose and take out one water molecule 768 00:22:53,610 --> 00:22:53,620 fructose and take out one water molecule 769 00:22:53,620 --> 00:22:56,950 fructose and take out one water molecule this is a gain of condensation right you 770 00:22:56,950 --> 00:22:56,960 this is a gain of condensation right you 771 00:22:56,960 --> 00:22:59,320 this is a gain of condensation right you take H from one side hydrogen from one 772 00:22:59,320 --> 00:22:59,330 take H from one side hydrogen from one 773 00:22:59,330 --> 00:23:01,299 take H from one side hydrogen from one side and one water molecule comes out 774 00:23:01,299 --> 00:23:01,309 side and one water molecule comes out 775 00:23:01,309 --> 00:23:06,190 side and one water molecule comes out and we get actually a disaccharide that 776 00:23:06,190 --> 00:23:06,200 and we get actually a disaccharide that 777 00:23:06,200 --> 00:23:08,950 and we get actually a disaccharide that means two monomers and this is sucrose 778 00:23:08,950 --> 00:23:08,960 means two monomers and this is sucrose 779 00:23:08,960 --> 00:23:11,740 means two monomers and this is sucrose this is the table sugar actually we have 780 00:23:11,740 --> 00:23:11,750 this is the table sugar actually we have 781 00:23:11,750 --> 00:23:13,710 this is the table sugar actually we have the glucose and fructose 782 00:23:13,710 --> 00:23:13,720 the glucose and fructose 783 00:23:13,720 --> 00:23:16,740 the glucose and fructose combined together now if we combine two 784 00:23:16,740 --> 00:23:16,750 combined together now if we combine two 785 00:23:16,750 --> 00:23:19,950 combined together now if we combine two glucose units together like this and it 786 00:23:19,950 --> 00:23:19,960 glucose units together like this and it 787 00:23:19,960 --> 00:23:22,440 glucose units together like this and it becomes a lactose it is also sugar but 788 00:23:22,440 --> 00:23:22,450 becomes a lactose it is also sugar but 789 00:23:22,450 --> 00:23:25,410 becomes a lactose it is also sugar but that is milk sugar right that is the 790 00:23:25,410 --> 00:23:25,420 that is milk sugar right that is the 791 00:23:25,420 --> 00:23:29,400 that is milk sugar right that is the milk sugar again now then we can add 792 00:23:29,400 --> 00:23:29,410 milk sugar again now then we can add 793 00:23:29,410 --> 00:23:32,310 milk sugar again now then we can add here more and more and make that chain 794 00:23:32,310 --> 00:23:32,320 here more and more and make that chain 795 00:23:32,320 --> 00:23:35,790 here more and more and make that chain more and more longer and longer actually 796 00:23:35,790 --> 00:23:35,800 more and more longer and longer actually 797 00:23:35,800 --> 00:23:38,520 more and more longer and longer actually and bigger and bigger molecule and then 798 00:23:38,520 --> 00:23:38,530 and bigger and bigger molecule and then 799 00:23:38,530 --> 00:23:41,390 and bigger and bigger molecule and then we simply have the polymers now 800 00:23:41,390 --> 00:23:41,400 we simply have the polymers now 801 00:23:41,400 --> 00:23:44,730 we simply have the polymers now polysaccharides as you can imagine means 802 00:23:44,730 --> 00:23:44,740 polysaccharides as you can imagine means 803 00:23:44,740 --> 00:23:46,440 polysaccharides as you can imagine means containing more than one of those 804 00:23:46,440 --> 00:23:46,450 containing more than one of those 805 00:23:46,450 --> 00:23:49,290 containing more than one of those glucose and fructose units as again 806 00:23:49,290 --> 00:23:49,300 glucose and fructose units as again 807 00:23:49,300 --> 00:23:52,230 glucose and fructose units as again linked together by condensation 808 00:23:52,230 --> 00:23:52,240 linked together by condensation 809 00:23:52,240 --> 00:23:55,200 linked together by condensation reactions and dehydration can create 810 00:23:55,200 --> 00:23:55,210 reactions and dehydration can create 811 00:23:55,210 --> 00:23:58,260 reactions and dehydration can create long-chain polysaccharides dehydration 812 00:23:58,260 --> 00:23:58,270 long-chain polysaccharides dehydration 813 00:23:58,270 --> 00:23:59,730 long-chain polysaccharides dehydration that's what the condensation reaction 814 00:23:59,730 --> 00:23:59,740 that's what the condensation reaction 815 00:23:59,740 --> 00:24:01,050 that's what the condensation reaction means take out the water 816 00:24:01,050 --> 00:24:01,060 means take out the water 817 00:24:01,060 --> 00:24:04,020 means take out the water dehydration means the three most common 818 00:24:04,020 --> 00:24:04,030 dehydration means the three most common 819 00:24:04,030 --> 00:24:08,090 dehydration means the three most common are the these polysaccharides starch 820 00:24:08,090 --> 00:24:08,100 are the these polysaccharides starch 821 00:24:08,100 --> 00:24:13,050 are the these polysaccharides starch glycogen and cellulose right and we know 822 00:24:13,050 --> 00:24:13,060 glycogen and cellulose right and we know 823 00:24:13,060 --> 00:24:18,600 glycogen and cellulose right and we know the starch we know the cellulose cotton 824 00:24:18,600 --> 00:24:18,610 the starch we know the cellulose cotton 825 00:24:18,610 --> 00:24:20,940 the starch we know the cellulose cotton and things like that right and glycogen 826 00:24:20,940 --> 00:24:20,950 and things like that right and glycogen 827 00:24:20,950 --> 00:24:24,000 and things like that right and glycogen czar in the animals these energy storage 828 00:24:24,000 --> 00:24:24,010 czar in the animals these energy storage 829 00:24:24,010 --> 00:24:27,900 czar in the animals these energy storage materials in the animals but even though 830 00:24:27,900 --> 00:24:27,910 materials in the animals but even though 831 00:24:27,910 --> 00:24:29,520 materials in the animals but even though they look like you have very different 832 00:24:29,520 --> 00:24:29,530 they look like you have very different 833 00:24:29,530 --> 00:24:31,890 they look like you have very different properties there are different functions 834 00:24:31,890 --> 00:24:31,900 properties there are different functions 835 00:24:31,900 --> 00:24:36,570 properties there are different functions also but chemically they are all made up 836 00:24:36,570 --> 00:24:36,580 also but chemically they are all made up 837 00:24:36,580 --> 00:24:39,720 also but chemically they are all made up from the same units that is the glucose 838 00:24:39,720 --> 00:24:39,730 from the same units that is the glucose 839 00:24:39,730 --> 00:24:43,920 from the same units that is the glucose or fructose or the other six membered 840 00:24:43,920 --> 00:24:43,930 or fructose or the other six membered 841 00:24:43,930 --> 00:24:47,130 or fructose or the other six membered sugar again right poly hydroxide 842 00:24:47,130 --> 00:24:47,140 sugar again right poly hydroxide 843 00:24:47,140 --> 00:24:49,440 sugar again right poly hydroxide now Sarge consists of many different 844 00:24:49,440 --> 00:24:49,450 now Sarge consists of many different 845 00:24:49,450 --> 00:24:53,040 now Sarge consists of many different size and various branch and chains of 846 00:24:53,040 --> 00:24:53,050 size and various branch and chains of 847 00:24:53,050 --> 00:24:55,800 size and various branch and chains of glucose prepared by plans to store 848 00:24:55,800 --> 00:24:55,810 glucose prepared by plans to store 849 00:24:55,810 --> 00:24:59,220 glucose prepared by plans to store energy so again the starch is used for 850 00:24:59,220 --> 00:24:59,230 energy so again the starch is used for 851 00:24:59,230 --> 00:25:01,830 energy so again the starch is used for the plant to store the energy and it's 852 00:25:01,830 --> 00:25:01,840 the plant to store the energy and it's 853 00:25:01,840 --> 00:25:03,990 the plant to store the energy and it's we also get our energy from the starch 854 00:25:03,990 --> 00:25:04,000 we also get our energy from the starch 855 00:25:04,000 --> 00:25:07,110 we also get our energy from the starch to from what we eat potatoes we eat rice 856 00:25:07,110 --> 00:25:07,120 to from what we eat potatoes we eat rice 857 00:25:07,120 --> 00:25:10,650 to from what we eat potatoes we eat rice we eat wheat and all of those contain a 858 00:25:10,650 --> 00:25:10,660 we eat wheat and all of those contain a 859 00:25:10,660 --> 00:25:14,900 we eat wheat and all of those contain a lot of starch and our body simply 860 00:25:14,900 --> 00:25:14,910 lot of starch and our body simply 861 00:25:14,910 --> 00:25:17,580 lot of starch and our body simply hydrolyzes that starch because the 862 00:25:17,580 --> 00:25:17,590 hydrolyzes that starch because the 863 00:25:17,590 --> 00:25:19,760 hydrolyzes that starch because the enzymes that we have in our body 864 00:25:19,760 --> 00:25:19,770 enzymes that we have in our body 865 00:25:19,770 --> 00:25:22,610 enzymes that we have in our body hydrolyzes that starts converts that 866 00:25:22,610 --> 00:25:22,620 hydrolyzes that starts converts that 867 00:25:22,620 --> 00:25:25,440 hydrolyzes that starts converts that polysaccharide into the glucose and 868 00:25:25,440 --> 00:25:25,450 polysaccharide into the glucose and 869 00:25:25,450 --> 00:25:27,150 polysaccharide into the glucose and fructose right 870 00:25:27,150 --> 00:25:27,160 fructose right 871 00:25:27,160 --> 00:25:29,880 fructose right all units and those smaller units are 872 00:25:29,880 --> 00:25:29,890 all units and those smaller units are 873 00:25:29,890 --> 00:25:33,450 all units and those smaller units are simply carried out and combusted in our 874 00:25:33,450 --> 00:25:33,460 simply carried out and combusted in our 875 00:25:33,460 --> 00:25:38,760 simply carried out and combusted in our body to create to to release the energy 876 00:25:38,760 --> 00:25:38,770 body to create to to release the energy 877 00:25:38,770 --> 00:25:43,020 body to create to to release the energy that we need for the survival right we 878 00:25:43,020 --> 00:25:43,030 that we need for the survival right we 879 00:25:43,030 --> 00:25:46,620 that we need for the survival right we need for the survival so glycogen is 880 00:25:46,620 --> 00:25:46,630 need for the survival so glycogen is 881 00:25:46,630 --> 00:25:48,900 need for the survival so glycogen is often called animal starch so it is 882 00:25:48,900 --> 00:25:48,910 often called animal starch so it is 883 00:25:48,910 --> 00:25:52,590 often called animal starch so it is similar to that again but animals have 884 00:25:52,590 --> 00:25:52,600 similar to that again but animals have 885 00:25:52,600 --> 00:25:54,540 similar to that again but animals have that glycogen or synthesizer collection 886 00:25:54,540 --> 00:25:54,550 that glycogen or synthesizer collection 887 00:25:54,550 --> 00:25:56,850 that glycogen or synthesizer collection it is far temporary energy storage in 888 00:25:56,850 --> 00:25:56,860 it is far temporary energy storage in 889 00:25:56,860 --> 00:25:58,670 it is far temporary energy storage in the animals it is called actually the 890 00:25:58,670 --> 00:25:58,680 the animals it is called actually the 891 00:25:58,680 --> 00:26:01,580 the animals it is called actually the energy bank of the animals 892 00:26:01,580 --> 00:26:01,590 energy bank of the animals 893 00:26:01,590 --> 00:26:04,680 energy bank of the animals fast for long-term energy storage again 894 00:26:04,680 --> 00:26:04,690 fast for long-term energy storage again 895 00:26:04,690 --> 00:26:07,500 fast for long-term energy storage again now cellulose is a structural 896 00:26:07,500 --> 00:26:07,510 now cellulose is a structural 897 00:26:07,510 --> 00:26:11,280 now cellulose is a structural polysaccharide in plants making up cell 898 00:26:11,280 --> 00:26:11,290 polysaccharide in plants making up cell 899 00:26:11,290 --> 00:26:12,210 polysaccharide in plants making up cell walls 900 00:26:12,210 --> 00:26:12,220 walls 901 00:26:12,220 --> 00:26:15,180 walls it is unbranched and particularly in 902 00:26:15,180 --> 00:26:15,190 it is unbranched and particularly in 903 00:26:15,190 --> 00:26:17,910 it is unbranched and particularly in plants it is making up cell walls and so 904 00:26:17,910 --> 00:26:17,920 plants it is making up cell walls and so 905 00:26:17,920 --> 00:26:20,880 plants it is making up cell walls and so on and it's unbranched now cellulose and 906 00:26:20,880 --> 00:26:20,890 on and it's unbranched now cellulose and 907 00:26:20,890 --> 00:26:24,320 on and it's unbranched now cellulose and starch are both made from glucose 908 00:26:24,320 --> 00:26:24,330 starch are both made from glucose 909 00:26:24,330 --> 00:26:28,770 starch are both made from glucose monosaccharide the same glucose but in 910 00:26:28,770 --> 00:26:28,780 monosaccharide the same glucose but in 911 00:26:28,780 --> 00:26:32,100 monosaccharide the same glucose but in one case we have alpha glucose in the 912 00:26:32,100 --> 00:26:32,110 one case we have alpha glucose in the 913 00:26:32,110 --> 00:26:34,680 one case we have alpha glucose in the other case we have beta glucose right 914 00:26:34,680 --> 00:26:34,690 other case we have beta glucose right 915 00:26:34,690 --> 00:26:38,240 other case we have beta glucose right that difference makes the starch and 916 00:26:38,240 --> 00:26:38,250 that difference makes the starch and 917 00:26:38,250 --> 00:26:41,670 that difference makes the starch and cellulose so different very very 918 00:26:41,670 --> 00:26:41,680 cellulose so different very very 919 00:26:41,680 --> 00:26:44,850 cellulose so different very very different actually now if we eat 920 00:26:44,850 --> 00:26:44,860 different actually now if we eat 921 00:26:44,860 --> 00:26:48,840 different actually now if we eat cellulose that will come out without 922 00:26:48,840 --> 00:26:48,850 cellulose that will come out without 923 00:26:48,850 --> 00:26:51,030 cellulose that will come out without digestion x' actually without any change 924 00:26:51,030 --> 00:26:51,040 digestion x' actually without any change 925 00:26:51,040 --> 00:26:53,730 digestion x' actually without any change you can just we can't do because we 926 00:26:53,730 --> 00:26:53,740 you can just we can't do because we 927 00:26:53,740 --> 00:26:57,600 you can just we can't do because we don't have enzymes to convert the 928 00:26:57,600 --> 00:26:57,610 don't have enzymes to convert the 929 00:26:57,610 --> 00:27:01,290 don't have enzymes to convert the cellulose into simple sugars those 930 00:27:01,290 --> 00:27:01,300 cellulose into simple sugars those 931 00:27:01,300 --> 00:27:04,740 cellulose into simple sugars those monomers but we have our enzymes convert 932 00:27:04,740 --> 00:27:04,750 monomers but we have our enzymes convert 933 00:27:04,750 --> 00:27:08,640 monomers but we have our enzymes convert the starch which is the same things to 934 00:27:08,640 --> 00:27:08,650 the starch which is the same things to 935 00:27:08,650 --> 00:27:10,710 the starch which is the same things to the sugar the difference is one is the 936 00:27:10,710 --> 00:27:10,720 the sugar the difference is one is the 937 00:27:10,720 --> 00:27:12,960 the sugar the difference is one is the alpha glucose the other one is beta 938 00:27:12,960 --> 00:27:12,970 alpha glucose the other one is beta 939 00:27:12,970 --> 00:27:15,330 alpha glucose the other one is beta glucose you see again the enzyme is so 940 00:27:15,330 --> 00:27:15,340 glucose you see again the enzyme is so 941 00:27:15,340 --> 00:27:19,560 glucose you see again the enzyme is so specific even that small difference make 942 00:27:19,560 --> 00:27:19,570 specific even that small difference make 943 00:27:19,570 --> 00:27:22,790 specific even that small difference make the enzyme non active it's not simply 944 00:27:22,790 --> 00:27:22,800 the enzyme non active it's not simply 945 00:27:22,800 --> 00:27:26,820 the enzyme non active it's not simply active at all in converting the human 946 00:27:26,820 --> 00:27:26,830 active at all in converting the human 947 00:27:26,830 --> 00:27:29,220 active at all in converting the human enzymes actually convert into cellulose 948 00:27:29,220 --> 00:27:29,230 enzymes actually convert into cellulose 949 00:27:29,230 --> 00:27:34,470 enzymes actually convert into cellulose to the sugar but the animals enzymes 950 00:27:34,470 --> 00:27:34,480 to the sugar but the animals enzymes 951 00:27:34,480 --> 00:27:37,680 to the sugar but the animals enzymes because they eat grass and that contains 952 00:27:37,680 --> 00:27:37,690 because they eat grass and that contains 953 00:27:37,690 --> 00:27:41,049 because they eat grass and that contains cellulose a lot of green things and can 954 00:27:41,049 --> 00:27:41,059 cellulose a lot of green things and can 955 00:27:41,059 --> 00:27:44,320 cellulose a lot of green things and can just that because their enzymes break 956 00:27:44,320 --> 00:27:44,330 just that because their enzymes break 957 00:27:44,330 --> 00:27:47,560 just that because their enzymes break the cellulose into monosaccharides and 958 00:27:47,560 --> 00:27:47,570 the cellulose into monosaccharides and 959 00:27:47,570 --> 00:27:49,690 the cellulose into monosaccharides and they can use up those in their bodies 960 00:27:49,690 --> 00:27:49,700 they can use up those in their bodies 961 00:27:49,700 --> 00:27:56,200 they can use up those in their bodies for the energy they needed okay these 962 00:27:56,200 --> 00:27:56,210 for the energy they needed okay these 963 00:27:56,210 --> 00:27:58,080 for the energy they needed okay these are the structures you see again 964 00:27:58,080 --> 00:27:58,090 are the structures you see again 965 00:27:58,090 --> 00:28:04,269 are the structures you see again polysaccharides here and I guess you can 966 00:28:04,269 --> 00:28:04,279 polysaccharides here and I guess you can 967 00:28:04,279 --> 00:28:07,090 polysaccharides here and I guess you can have single units like this or double 968 00:28:07,090 --> 00:28:07,100 have single units like this or double 969 00:28:07,100 --> 00:28:11,110 have single units like this or double like that and it is a polymer long-chain 970 00:28:11,110 --> 00:28:11,120 like that and it is a polymer long-chain 971 00:28:11,120 --> 00:28:15,269 like that and it is a polymer long-chain polymer you know very very big molecules 972 00:28:15,269 --> 00:28:15,279 polymer you know very very big molecules 973 00:28:15,279 --> 00:28:20,590 polymer you know very very big molecules now the others is the lipids the game 974 00:28:20,590 --> 00:28:20,600 now the others is the lipids the game 975 00:28:20,600 --> 00:28:24,879 now the others is the lipids the game now lipids are not polymers actually are 976 00:28:24,879 --> 00:28:24,889 now lipids are not polymers actually are 977 00:28:24,889 --> 00:28:28,749 now lipids are not polymers actually are not polymers lipids are broad class of 978 00:28:28,749 --> 00:28:28,759 not polymers lipids are broad class of 979 00:28:28,759 --> 00:28:31,180 not polymers lipids are broad class of nonpolar bio organic molecules they are 980 00:28:31,180 --> 00:28:31,190 nonpolar bio organic molecules they are 981 00:28:31,190 --> 00:28:33,369 nonpolar bio organic molecules they are grouped because they are insoluble in 982 00:28:33,369 --> 00:28:33,379 grouped because they are insoluble in 983 00:28:33,379 --> 00:28:37,600 grouped because they are insoluble in water now they are used biologically to 984 00:28:37,600 --> 00:28:37,610 water now they are used biologically to 985 00:28:37,610 --> 00:28:41,440 water now they are used biologically to store energy like fats and oils and for 986 00:28:41,440 --> 00:28:41,450 store energy like fats and oils and for 987 00:28:41,450 --> 00:28:45,100 store energy like fats and oils and for biological structures phospholipids in 988 00:28:45,100 --> 00:28:45,110 biological structures phospholipids in 989 00:28:45,110 --> 00:28:49,629 biological structures phospholipids in cell membranes now let's look at what is 990 00:28:49,629 --> 00:28:49,639 cell membranes now let's look at what is 991 00:28:49,639 --> 00:29:10,840 cell membranes now let's look at what is a fats and oil 992 00:29:10,840 --> 00:29:10,850 993 00:29:10,850 --> 00:29:21,110 now when we combine glycerol this is an 994 00:29:21,110 --> 00:29:21,120 now when we combine glycerol this is an 995 00:29:21,120 --> 00:29:32,150 now when we combine glycerol this is an alcohol plus three fatty acids and then 996 00:29:32,150 --> 00:29:32,160 alcohol plus three fatty acids and then 997 00:29:32,160 --> 00:29:39,380 alcohol plus three fatty acids and then we get the fat now what is a glycerol 998 00:29:39,380 --> 00:29:39,390 we get the fat now what is a glycerol 999 00:29:39,390 --> 00:29:42,310 we get the fat now what is a glycerol glycerol is is the structure actually 1000 00:29:42,310 --> 00:29:42,320 glycerol is is the structure actually 1001 00:29:42,320 --> 00:29:50,030 glycerol is is the structure actually three carbons and I have an IH o H and O 1002 00:29:50,030 --> 00:29:50,040 three carbons and I have an IH o H and O 1003 00:29:50,040 --> 00:29:54,110 three carbons and I have an IH o H and O H here and then two hydrogen's one 1004 00:29:54,110 --> 00:29:54,120 H here and then two hydrogen's one 1005 00:29:54,120 --> 00:29:57,560 H here and then two hydrogen's one hydrogen and two hydrogen there now when 1006 00:29:57,560 --> 00:29:57,570 hydrogen and two hydrogen there now when 1007 00:29:57,570 --> 00:29:59,480 hydrogen and two hydrogen there now when we combine it with fatty acids what is 1008 00:29:59,480 --> 00:29:59,490 we combine it with fatty acids what is 1009 00:29:59,490 --> 00:30:01,520 we combine it with fatty acids what is the fatty acids fatty acids is actually 1010 00:30:01,520 --> 00:30:01,530 the fatty acids fatty acids is actually 1011 00:30:01,530 --> 00:30:04,610 the fatty acids fatty acids is actually carboxylic acids long chain number of 1012 00:30:04,610 --> 00:30:04,620 carboxylic acids long chain number of 1013 00:30:04,620 --> 00:30:08,750 carboxylic acids long chain number of carbon is between 16 and 19 right so we 1014 00:30:08,750 --> 00:30:08,760 carbon is between 16 and 19 right so we 1015 00:30:08,760 --> 00:30:12,799 carbon is between 16 and 19 right so we simply have let's say CH 3 and then 1016 00:30:12,799 --> 00:30:12,809 simply have let's say CH 3 and then 1017 00:30:12,809 --> 00:30:17,060 simply have let's say CH 3 and then let's call here CH 2 and make that one 1018 00:30:17,060 --> 00:30:17,070 let's call here CH 2 and make that one 1019 00:30:17,070 --> 00:30:25,330 let's call here CH 2 and make that one let's make that 16 plus C oh oh and co h 1020 00:30:25,330 --> 00:30:25,340 let's make that 16 plus C oh oh and co h 1021 00:30:25,340 --> 00:30:28,549 let's make that 16 plus C oh oh and co h this is the fatty acids again how many 1022 00:30:28,549 --> 00:30:28,559 this is the fatty acids again how many 1023 00:30:28,559 --> 00:30:32,870 this is the fatty acids again how many carbons this says 16 17 18 carbons may 1024 00:30:32,870 --> 00:30:32,880 carbons this says 16 17 18 carbons may 1025 00:30:32,880 --> 00:30:36,200 carbons this says 16 17 18 carbons may be up to 8 19 carbons now if you get 1026 00:30:36,200 --> 00:30:36,210 be up to 8 19 carbons now if you get 1027 00:30:36,210 --> 00:30:40,570 be up to 8 19 carbons now if you get three of those and we get the 1028 00:30:40,570 --> 00:30:40,580 three of those and we get the 1029 00:30:40,580 --> 00:30:43,159 three of those and we get the esterification x' actually we get the 1030 00:30:43,159 --> 00:30:43,169 esterification x' actually we get the 1031 00:30:43,169 --> 00:30:48,200 esterification x' actually we get the esters and this simply Oh H takes out 1032 00:30:48,200 --> 00:30:48,210 esters and this simply Oh H takes out 1033 00:30:48,210 --> 00:30:50,450 esters and this simply Oh H takes out one of that hydrogen's and then we end 1034 00:30:50,450 --> 00:30:50,460 one of that hydrogen's and then we end 1035 00:30:50,460 --> 00:31:35,930 one of that hydrogen's and then we end up with this 1036 00:31:35,930 --> 00:31:35,940 1037 00:31:35,940 --> 00:31:39,800 all right this is the fat and plus we 1038 00:31:39,800 --> 00:31:39,810 all right this is the fat and plus we 1039 00:31:39,810 --> 00:31:42,140 all right this is the fat and plus we have two three water molecules right 1040 00:31:42,140 --> 00:31:42,150 have two three water molecules right 1041 00:31:42,150 --> 00:31:45,860 have two three water molecules right coming out there this is what we call a 1042 00:31:45,860 --> 00:31:45,870 coming out there this is what we call a 1043 00:31:45,870 --> 00:31:55,430 coming out there this is what we call a fat now depending on the fatty acids 1044 00:31:55,430 --> 00:31:55,440 fat now depending on the fatty acids 1045 00:31:55,440 --> 00:31:59,870 fat now depending on the fatty acids actually carboxylic acid these are long 1046 00:31:59,870 --> 00:31:59,880 actually carboxylic acid these are long 1047 00:31:59,880 --> 00:32:02,180 actually carboxylic acid these are long carboxylic acid if it contains a double 1048 00:32:02,180 --> 00:32:02,190 carboxylic acid if it contains a double 1049 00:32:02,190 --> 00:32:06,770 carboxylic acid if it contains a double bond then we have the unsaturated fat 1050 00:32:06,770 --> 00:32:06,780 bond then we have the unsaturated fat 1051 00:32:06,780 --> 00:32:09,440 bond then we have the unsaturated fat and if it's all saturated then we have a 1052 00:32:09,440 --> 00:32:09,450 and if it's all saturated then we have a 1053 00:32:09,450 --> 00:32:11,330 and if it's all saturated then we have a saturated fat but this is what the fat 1054 00:32:11,330 --> 00:32:11,340 saturated fat but this is what the fat 1055 00:32:11,340 --> 00:32:14,810 saturated fat but this is what the fat is all about a glycerol and those fatty 1056 00:32:14,810 --> 00:32:14,820 is all about a glycerol and those fatty 1057 00:32:14,820 --> 00:32:18,490 is all about a glycerol and those fatty acids that's all it is 1058 00:32:18,490 --> 00:32:18,500 1059 00:32:18,500 --> 00:32:22,070 let's look at here is what says fats and 1060 00:32:22,070 --> 00:32:22,080 let's look at here is what says fats and 1061 00:32:22,080 --> 00:32:25,310 let's look at here is what says fats and oils are made from long-chain carboxylic 1062 00:32:25,310 --> 00:32:25,320 oils are made from long-chain carboxylic 1063 00:32:25,320 --> 00:32:28,040 oils are made from long-chain carboxylic acids and glycerol actually when we say 1064 00:32:28,040 --> 00:32:28,050 acids and glycerol actually when we say 1065 00:32:28,050 --> 00:32:31,030 acids and glycerol actually when we say oil that means it contains unsaturated 1066 00:32:31,030 --> 00:32:31,040 oil that means it contains unsaturated 1067 00:32:31,040 --> 00:32:34,070 oil that means it contains unsaturated carbonyl unsaturated carbons if it all 1068 00:32:34,070 --> 00:32:34,080 carbonyl unsaturated carbons if it all 1069 00:32:34,080 --> 00:32:37,280 carbonyl unsaturated carbons if it all saturated we call it fat like this are 1070 00:32:37,280 --> 00:32:37,290 saturated we call it fat like this are 1071 00:32:37,290 --> 00:32:39,800 saturated we call it fat like this are made from long-chain carboxylic acid and 1072 00:32:39,800 --> 00:32:39,810 made from long-chain carboxylic acid and 1073 00:32:39,810 --> 00:32:41,900 made from long-chain carboxylic acid and glycerol this is the long-chain 1074 00:32:41,900 --> 00:32:41,910 glycerol this is the long-chain 1075 00:32:41,910 --> 00:32:44,840 glycerol this is the long-chain carboxylic acid and this is the glycerol 1076 00:32:44,840 --> 00:32:44,850 carboxylic acid and this is the glycerol 1077 00:32:44,850 --> 00:32:45,740 carboxylic acid and this is the glycerol right 1078 00:32:45,740 --> 00:32:45,750 right 1079 00:32:45,750 --> 00:32:49,550 right glycerol now fats have only saturated 1080 00:32:49,550 --> 00:32:49,560 glycerol now fats have only saturated 1081 00:32:49,560 --> 00:32:52,550 glycerol now fats have only saturated carboxylic acids and they are solids 1082 00:32:52,550 --> 00:32:52,560 carboxylic acids and they are solids 1083 00:32:52,560 --> 00:32:55,970 carboxylic acids and they are solids these are often called the bad fats in 1084 00:32:55,970 --> 00:32:55,980 these are often called the bad fats in 1085 00:32:55,980 --> 00:32:58,310 these are often called the bad fats in your diet you know you don't want the 1086 00:32:58,310 --> 00:32:58,320 your diet you know you don't want the 1087 00:32:58,320 --> 00:33:01,150 your diet you know you don't want the saturated one but we want these 1088 00:33:01,150 --> 00:33:01,160 saturated one but we want these 1089 00:33:01,160 --> 00:33:05,420 saturated one but we want these unsaturated ones oils have at least one 1090 00:33:05,420 --> 00:33:05,430 unsaturated ones oils have at least one 1091 00:33:05,430 --> 00:33:08,300 unsaturated ones oils have at least one unsaturated carboxylic acids they are 1092 00:33:08,300 --> 00:33:08,310 unsaturated carboxylic acids they are 1093 00:33:08,310 --> 00:33:11,330 unsaturated carboxylic acids they are liquids the more unsaturated the better 1094 00:33:11,330 --> 00:33:11,340 liquids the more unsaturated the better 1095 00:33:11,340 --> 00:33:14,870 liquids the more unsaturated the better for poly for you that means 1096 00:33:14,870 --> 00:33:14,880 for poly for you that means 1097 00:33:14,880 --> 00:33:16,700 for poly for you that means polyunsaturated versus monounsaturated 1098 00:33:16,700 --> 00:33:16,710 polyunsaturated versus monounsaturated 1099 00:33:16,710 --> 00:33:20,450 polyunsaturated versus monounsaturated fats we also have that now essentially 1100 00:33:20,450 --> 00:33:20,460 fats we also have that now essentially 1101 00:33:20,460 --> 00:33:23,330 fats we also have that now essentially fatty acids with double bonds must be 1102 00:33:23,330 --> 00:33:23,340 fatty acids with double bonds must be 1103 00:33:23,340 --> 00:33:26,450 fatty acids with double bonds must be included in our diet our bodies cannot 1104 00:33:26,450 --> 00:33:26,460 included in our diet our bodies cannot 1105 00:33:26,460 --> 00:33:30,790 included in our diet our bodies cannot produce them they are often called 1106 00:33:30,790 --> 00:33:30,800 produce them they are often called 1107 00:33:30,800 --> 00:33:34,940 produce them they are often called omega-3 and omega-6 fatty acids okay 1108 00:33:34,940 --> 00:33:34,950 omega-3 and omega-6 fatty acids okay 1109 00:33:34,950 --> 00:33:38,900 omega-3 and omega-6 fatty acids okay here is the things now remember the we 1110 00:33:38,900 --> 00:33:38,910 here is the things now remember the we 1111 00:33:38,910 --> 00:33:42,290 here is the things now remember the we say the omega-3 which the fish oil 1112 00:33:42,290 --> 00:33:42,300 say the omega-3 which the fish oil 1113 00:33:42,300 --> 00:33:45,140 say the omega-3 which the fish oil contains a lot of omega-3 and very very 1114 00:33:45,140 --> 00:33:45,150 contains a lot of omega-3 and very very 1115 00:33:45,150 --> 00:33:47,960 contains a lot of omega-3 and very very useful for health in fact right good 1116 00:33:47,960 --> 00:33:47,970 useful for health in fact right good 1117 00:33:47,970 --> 00:33:49,700 useful for health in fact right good food the 1118 00:33:49,700 --> 00:33:49,710 food the 1119 00:33:49,710 --> 00:33:52,940 food the omega-3 are the oils which have 1120 00:33:52,940 --> 00:33:52,950 omega-3 are the oils which have 1121 00:33:52,950 --> 00:33:56,840 omega-3 are the oils which have unsaturated hydrocarbons from this end 1122 00:33:56,840 --> 00:33:56,850 unsaturated hydrocarbons from this end 1123 00:33:56,850 --> 00:33:59,840 unsaturated hydrocarbons from this end in the third hydrocarbon that's the 1124 00:33:59,840 --> 00:33:59,850 in the third hydrocarbon that's the 1125 00:33:59,850 --> 00:34:02,570 in the third hydrocarbon that's the Omega third carbon this is the first 1126 00:34:02,570 --> 00:34:02,580 Omega third carbon this is the first 1127 00:34:02,580 --> 00:34:05,779 Omega third carbon this is the first carbon second third if you have a double 1128 00:34:05,779 --> 00:34:05,789 carbon second third if you have a double 1129 00:34:05,789 --> 00:34:07,130 carbon second third if you have a double bond between third and fourth carbon 1130 00:34:07,130 --> 00:34:07,140 bond between third and fourth carbon 1131 00:34:07,140 --> 00:34:09,710 bond between third and fourth carbon here in this chain and here and here 1132 00:34:09,710 --> 00:34:09,720 here in this chain and here and here 1133 00:34:09,720 --> 00:34:13,339 here in this chain and here and here that's called the omega-3 oil right 1134 00:34:13,339 --> 00:34:13,349 that's called the omega-3 oil right 1135 00:34:13,349 --> 00:34:16,579 that's called the omega-3 oil right omega-3 oil now if I have the double 1136 00:34:16,579 --> 00:34:16,589 omega-3 oil now if I have the double 1137 00:34:16,589 --> 00:34:19,639 omega-3 oil now if I have the double bond on six carbon from this end it is 1138 00:34:19,639 --> 00:34:19,649 bond on six carbon from this end it is 1139 00:34:19,649 --> 00:34:23,060 bond on six carbon from this end it is called omega-6 and these omega-3 on over 1140 00:34:23,060 --> 00:34:23,070 called omega-6 and these omega-3 on over 1141 00:34:23,070 --> 00:34:28,190 called omega-6 and these omega-3 on over six are the oils that we meet and they 1142 00:34:28,190 --> 00:34:28,200 six are the oils that we meet and they 1143 00:34:28,200 --> 00:34:30,970 six are the oils that we meet and they have to be taken outside they have to be 1144 00:34:30,970 --> 00:34:30,980 have to be taken outside they have to be 1145 00:34:30,980 --> 00:34:34,550 have to be taken outside they have to be ingested that means we have to eat food 1146 00:34:34,550 --> 00:34:34,560 ingested that means we have to eat food 1147 00:34:34,560 --> 00:34:41,320 ingested that means we have to eat food containing these omega-3 and omega-6 and 1148 00:34:41,320 --> 00:34:41,330 containing these omega-3 and omega-6 and 1149 00:34:41,330 --> 00:34:47,300 containing these omega-3 and omega-6 and now our phospholipids are similar type 1150 00:34:47,300 --> 00:34:47,310 now our phospholipids are similar type 1151 00:34:47,310 --> 00:34:49,300 now our phospholipids are similar type structure let's see how they are 1152 00:34:49,300 --> 00:34:49,310 structure let's see how they are 1153 00:34:49,310 --> 00:34:52,070 structure let's see how they are arranged again you see how their 1154 00:34:52,070 --> 00:34:52,080 arranged again you see how their 1155 00:34:52,080 --> 00:34:54,440 arranged again you see how their structures is similar to the facts we 1156 00:34:54,440 --> 00:34:54,450 structures is similar to the facts we 1157 00:34:54,450 --> 00:34:57,050 structures is similar to the facts we have the glycerol with ester linkage to 1158 00:34:57,050 --> 00:34:57,060 have the glycerol with ester linkage to 1159 00:34:57,060 --> 00:35:00,349 have the glycerol with ester linkage to two fatty acids instead of three okay 1160 00:35:00,349 --> 00:35:00,359 two fatty acids instead of three okay 1161 00:35:00,359 --> 00:35:05,839 two fatty acids instead of three okay now for the lipids actually like here in 1162 00:35:05,839 --> 00:35:05,849 now for the lipids actually like here in 1163 00:35:05,849 --> 00:35:10,849 now for the lipids actually like here in this formula we have three acids fatty 1164 00:35:10,849 --> 00:35:10,859 this formula we have three acids fatty 1165 00:35:10,859 --> 00:35:14,450 this formula we have three acids fatty acids here but in the lipids we have 250 1166 00:35:14,450 --> 00:35:14,460 acids here but in the lipids we have 250 1167 00:35:14,460 --> 00:35:16,329 acids here but in the lipids we have 250 edges but here we have the phosphate 1168 00:35:16,329 --> 00:35:16,339 edges but here we have the phosphate 1169 00:35:16,339 --> 00:35:19,490 edges but here we have the phosphate group here to fatty edges and one 1170 00:35:19,490 --> 00:35:19,500 group here to fatty edges and one 1171 00:35:19,500 --> 00:35:21,859 group here to fatty edges and one phosphate group and that makes the lipid 1172 00:35:21,859 --> 00:35:21,869 phosphate group and that makes the lipid 1173 00:35:21,869 --> 00:35:27,170 phosphate group and that makes the lipid actually how it differs the third side 1174 00:35:27,170 --> 00:35:27,180 actually how it differs the third side 1175 00:35:27,180 --> 00:35:30,890 actually how it differs the third side has a phosphate ester linkage connected 1176 00:35:30,890 --> 00:35:30,900 has a phosphate ester linkage connected 1177 00:35:30,900 --> 00:35:33,339 has a phosphate ester linkage connected to the charge or polar group such as 1178 00:35:33,339 --> 00:35:33,349 to the charge or polar group such as 1179 00:35:33,349 --> 00:35:38,930 to the charge or polar group such as choline and that end actually which 1180 00:35:38,930 --> 00:35:38,940 choline and that end actually which 1181 00:35:38,940 --> 00:35:41,060 choline and that end actually which contains a phosphate is a charge and 1182 00:35:41,060 --> 00:35:41,070 contains a phosphate is a charge and 1183 00:35:41,070 --> 00:35:45,109 contains a phosphate is a charge and polar type side of the lipid molecule 1184 00:35:45,109 --> 00:35:45,119 polar type side of the lipid molecule 1185 00:35:45,119 --> 00:35:47,960 polar type side of the lipid molecule the clustered together in water polar 1186 00:35:47,960 --> 00:35:47,970 the clustered together in water polar 1187 00:35:47,970 --> 00:35:50,349 the clustered together in water polar regions they cluster together in water 1188 00:35:50,349 --> 00:35:50,359 regions they cluster together in water 1189 00:35:50,359 --> 00:35:53,720 regions they cluster together in water such as polar regions pointing toward 1190 00:35:53,720 --> 00:35:53,730 such as polar regions pointing toward 1191 00:35:53,730 --> 00:35:56,060 such as polar regions pointing toward the water and nonpolar fatty acids 1192 00:35:56,060 --> 00:35:56,070 the water and nonpolar fatty acids 1193 00:35:56,070 --> 00:35:57,980 the water and nonpolar fatty acids regions pointing toward each other 1194 00:35:57,980 --> 00:35:57,990 regions pointing toward each other 1195 00:35:57,990 --> 00:36:02,660 regions pointing toward each other forming a lipid by layer and the start 1196 00:36:02,660 --> 00:36:02,670 forming a lipid by layer and the start 1197 00:36:02,670 --> 00:36:03,320 forming a lipid by layer and the start of 1198 00:36:03,320 --> 00:36:03,330 of 1199 00:36:03,330 --> 00:36:05,480 of cell membrane the cell membrane is made 1200 00:36:05,480 --> 00:36:05,490 cell membrane the cell membrane is made 1201 00:36:05,490 --> 00:36:09,110 cell membrane the cell membrane is made of like this again in this case we have 1202 00:36:09,110 --> 00:36:09,120 of like this again in this case we have 1203 00:36:09,120 --> 00:36:12,410 of like this again in this case we have the water polar side and ionic side in 1204 00:36:12,410 --> 00:36:12,420 the water polar side and ionic side in 1205 00:36:12,420 --> 00:36:14,480 the water polar side and ionic side in the water side and this is the ionic 1206 00:36:14,480 --> 00:36:14,490 the water side and this is the ionic 1207 00:36:14,490 --> 00:36:17,180 the water side and this is the ionic side here and the nonpolar side and 1208 00:36:17,180 --> 00:36:17,190 side here and the nonpolar side and 1209 00:36:17,190 --> 00:36:19,280 side here and the nonpolar side and organic part hydrocarbon parts is inside 1210 00:36:19,280 --> 00:36:19,290 organic part hydrocarbon parts is inside 1211 00:36:19,290 --> 00:36:22,250 organic part hydrocarbon parts is inside so we have sort of a layer and which is 1212 00:36:22,250 --> 00:36:22,260 so we have sort of a layer and which is 1213 00:36:22,260 --> 00:36:27,980 so we have sort of a layer and which is the structure of the membrane of the 1214 00:36:27,980 --> 00:36:27,990 the structure of the membrane of the 1215 00:36:27,990 --> 00:36:30,800 the structure of the membrane of the cells is similar to that and we have 1216 00:36:30,800 --> 00:36:30,810 cells is similar to that and we have 1217 00:36:30,810 --> 00:36:32,960 cells is similar to that and we have water and water here inside and outside 1218 00:36:32,960 --> 00:36:32,970 water and water here inside and outside 1219 00:36:32,970 --> 00:36:35,870 water and water here inside and outside of the cell and that is the lipid very 1220 00:36:35,870 --> 00:36:35,880 of the cell and that is the lipid very 1221 00:36:35,880 --> 00:36:38,270 of the cell and that is the lipid very very important structure part of the 1222 00:36:38,270 --> 00:36:38,280 very important structure part of the 1223 00:36:38,280 --> 00:36:46,190 very important structure part of the cell living cells yes here is the 1224 00:36:46,190 --> 00:36:46,200 cell living cells yes here is the 1225 00:36:46,200 --> 00:36:50,980 cell living cells yes here is the example again this is the fatty acids 1226 00:36:50,980 --> 00:36:50,990 example again this is the fatty acids 1227 00:36:50,990 --> 00:36:53,390 example again this is the fatty acids fat actually I should say there are 1228 00:36:53,390 --> 00:36:53,400 fat actually I should say there are 1229 00:36:53,400 --> 00:36:55,580 fat actually I should say there are fatty acids and that is the same as this 1230 00:36:55,580 --> 00:36:55,590 fatty acids and that is the same as this 1231 00:36:55,590 --> 00:36:57,950 fatty acids and that is the same as this right over here just the open formula 1232 00:36:57,950 --> 00:36:57,960 right over here just the open formula 1233 00:36:57,960 --> 00:37:01,100 right over here just the open formula and how many carbons I don't know but it 1234 00:37:01,100 --> 00:37:01,110 and how many carbons I don't know but it 1235 00:37:01,110 --> 00:37:03,410 and how many carbons I don't know but it right down the carbons like this and 1236 00:37:03,410 --> 00:37:03,420 right down the carbons like this and 1237 00:37:03,420 --> 00:37:07,070 right down the carbons like this and there is no unsaturated here so that 1238 00:37:07,070 --> 00:37:07,080 there is no unsaturated here so that 1239 00:37:07,080 --> 00:37:09,260 there is no unsaturated here so that means this is going to be a fat from 1240 00:37:09,260 --> 00:37:09,270 means this is going to be a fat from 1241 00:37:09,270 --> 00:37:11,180 means this is going to be a fat from fatty acids palmitic acid this is a 1242 00:37:11,180 --> 00:37:11,190 fatty acids palmitic acid this is a 1243 00:37:11,190 --> 00:37:13,880 fatty acids palmitic acid this is a polymeric acid now when we have a lipid 1244 00:37:13,880 --> 00:37:13,890 polymeric acid now when we have a lipid 1245 00:37:13,890 --> 00:37:17,960 polymeric acid now when we have a lipid and we have two acids just like here two 1246 00:37:17,960 --> 00:37:17,970 and we have two acids just like here two 1247 00:37:17,970 --> 00:37:21,340 and we have two acids just like here two of those the third one is the phosphate 1248 00:37:21,340 --> 00:37:21,350 of those the third one is the phosphate 1249 00:37:21,350 --> 00:37:25,370 of those the third one is the phosphate bond it over here like this and this is 1250 00:37:25,370 --> 00:37:25,380 bond it over here like this and this is 1251 00:37:25,380 --> 00:37:27,770 bond it over here like this and this is the polar part there's some something 1252 00:37:27,770 --> 00:37:27,780 the polar part there's some something 1253 00:37:27,780 --> 00:37:29,990 the polar part there's some something wrong here this is going to be CH 3 1254 00:37:29,990 --> 00:37:30,000 wrong here this is going to be CH 3 1255 00:37:30,000 --> 00:37:33,860 wrong here this is going to be CH 3 times 3 not ch2 but that is a positive 1256 00:37:33,860 --> 00:37:33,870 times 3 not ch2 but that is a positive 1257 00:37:33,870 --> 00:37:35,450 times 3 not ch2 but that is a positive side there is a negative side here this 1258 00:37:35,450 --> 00:37:35,460 side there is a negative side here this 1259 00:37:35,460 --> 00:37:37,970 side there is a negative side here this is a polar part that part is the one 1260 00:37:37,970 --> 00:37:37,980 is a polar part that part is the one 1261 00:37:37,980 --> 00:37:41,480 is a polar part that part is the one which is in the water side and this part 1262 00:37:41,480 --> 00:37:41,490 which is in the water side and this part 1263 00:37:41,490 --> 00:37:46,220 which is in the water side and this part is in inside of that lipid structure 1264 00:37:46,220 --> 00:37:46,230 is in inside of that lipid structure 1265 00:37:46,230 --> 00:37:49,910 is in inside of that lipid structure that we have seen yes this one over here 1266 00:37:49,910 --> 00:37:49,920 that we have seen yes this one over here 1267 00:37:49,920 --> 00:37:52,730 that we have seen yes this one over here this is the polar part and this is the 1268 00:37:52,730 --> 00:37:52,740 this is the polar part and this is the 1269 00:37:52,740 --> 00:37:59,900 this is the polar part and this is the nonpolar part of the lipid and that's 1270 00:37:59,900 --> 00:37:59,910 nonpolar part of the lipid and that's 1271 00:37:59,910 --> 00:38:04,760 nonpolar part of the lipid and that's called the phospholipids this is the fat 1272 00:38:04,760 --> 00:38:04,770 called the phospholipids this is the fat 1273 00:38:04,770 --> 00:38:07,550 called the phospholipids this is the fat and this is the lipid and if I have a 1274 00:38:07,550 --> 00:38:07,560 and this is the lipid and if I have a 1275 00:38:07,560 --> 00:38:09,470 and this is the lipid and if I have a double bond here then it becomes oil 1276 00:38:09,470 --> 00:38:09,480 double bond here then it becomes oil 1277 00:38:09,480 --> 00:38:15,470 double bond here then it becomes oil right becomes oil 1278 00:38:15,470 --> 00:38:15,480 1279 00:38:15,480 --> 00:38:20,210 nucleic acids are another type of 1280 00:38:20,210 --> 00:38:20,220 nucleic acids are another type of 1281 00:38:20,220 --> 00:38:25,380 nucleic acids are another type of biopolymers very very important class of 1282 00:38:25,380 --> 00:38:25,390 biopolymers very very important class of 1283 00:38:25,390 --> 00:38:28,170 biopolymers very very important class of biopolymers that are chemically carriers 1284 00:38:28,170 --> 00:38:28,180 biopolymers that are chemically carriers 1285 00:38:28,180 --> 00:38:31,200 biopolymers that are chemically carriers of genetic information this is very very 1286 00:38:31,200 --> 00:38:31,210 of genetic information this is very very 1287 00:38:31,210 --> 00:38:33,809 of genetic information this is very very important as a matter of fact they carry 1288 00:38:33,809 --> 00:38:33,819 important as a matter of fact they carry 1289 00:38:33,819 --> 00:38:35,910 important as a matter of fact they carry out the genetic information and there 1290 00:38:35,910 --> 00:38:35,920 out the genetic information and there 1291 00:38:35,920 --> 00:38:39,470 out the genetic information and there are two types one is deoxy carbo 1292 00:38:39,470 --> 00:38:39,480 are two types one is deoxy carbo 1293 00:38:39,480 --> 00:38:42,390 are two types one is deoxy carbo ribonucleic acid which is abbreviation 1294 00:38:42,390 --> 00:38:42,400 ribonucleic acid which is abbreviation 1295 00:38:42,400 --> 00:38:44,970 ribonucleic acid which is abbreviation for this is DNA and this is ribonucleic 1296 00:38:44,970 --> 00:38:44,980 for this is DNA and this is ribonucleic 1297 00:38:44,980 --> 00:38:48,120 for this is DNA and this is ribonucleic acid the abbreviations is RNA very close 1298 00:38:48,120 --> 00:38:48,130 acid the abbreviations is RNA very close 1299 00:38:48,130 --> 00:38:50,339 acid the abbreviations is RNA very close structures I will show you how they 1300 00:38:50,339 --> 00:38:50,349 structures I will show you how they 1301 00:38:50,349 --> 00:38:53,849 structures I will show you how they differ actually okay let's look at the 1302 00:38:53,849 --> 00:38:53,859 differ actually okay let's look at the 1303 00:38:53,859 --> 00:39:00,000 differ actually okay let's look at the RNA and DNA nucleic acid types in a DNA 1304 00:39:00,000 --> 00:39:00,010 RNA and DNA nucleic acid types in a DNA 1305 00:39:00,010 --> 00:39:03,960 RNA and DNA nucleic acid types in a DNA we have huge molecules six to 16 million 1306 00:39:03,960 --> 00:39:03,970 we have huge molecules six to 16 million 1307 00:39:03,970 --> 00:39:08,460 we have huge molecules six to 16 million atomic mass unit really long chain long 1308 00:39:08,460 --> 00:39:08,470 atomic mass unit really long chain long 1309 00:39:08,470 --> 00:39:11,790 atomic mass unit really long chain long chains and then here we have smaller 1310 00:39:11,790 --> 00:39:11,800 chains and then here we have smaller 1311 00:39:11,800 --> 00:39:13,890 chains and then here we have smaller molecules RNA are smaller but when we 1312 00:39:13,890 --> 00:39:13,900 molecules RNA are smaller but when we 1313 00:39:13,900 --> 00:39:16,309 molecules RNA are smaller but when we say smaller the atomic mass unit is from 1314 00:39:16,309 --> 00:39:16,319 say smaller the atomic mass unit is from 1315 00:39:16,319 --> 00:39:19,530 say smaller the atomic mass unit is from 20,000 to 40,000 years can you imagine 1316 00:39:19,530 --> 00:39:19,540 20,000 to 40,000 years can you imagine 1317 00:39:19,540 --> 00:39:23,730 20,000 to 40,000 years can you imagine and now one mole of this substance will 1318 00:39:23,730 --> 00:39:23,740 and now one mole of this substance will 1319 00:39:23,740 --> 00:39:26,160 and now one mole of this substance will be how many grams can you tell me one 1320 00:39:26,160 --> 00:39:26,170 be how many grams can you tell me one 1321 00:39:26,170 --> 00:39:28,890 be how many grams can you tell me one mole of RNA if the atomic mass is 40,000 1322 00:39:28,890 --> 00:39:28,900 mole of RNA if the atomic mass is 40,000 1323 00:39:28,900 --> 00:39:35,970 mole of RNA if the atomic mass is 40,000 how many what is the mass one mole 40 1324 00:39:35,970 --> 00:39:35,980 how many what is the mass one mole 40 1325 00:39:35,980 --> 00:39:38,760 how many what is the mass one mole 40 kilograms right one mole is 40 kilograms 1326 00:39:38,760 --> 00:39:38,770 kilograms right one mole is 40 kilograms 1327 00:39:38,770 --> 00:39:43,339 kilograms right one mole is 40 kilograms now if you come over here I guess Oh 1328 00:39:43,339 --> 00:39:43,349 now if you come over here I guess Oh 1329 00:39:43,349 --> 00:39:49,980 now if you come over here I guess Oh sixteen million one mole will be 16 1330 00:39:49,980 --> 00:39:49,990 sixteen million one mole will be 16 1331 00:39:49,990 --> 00:39:51,329 sixteen million one mole will be 16 tonnes or something like that 1332 00:39:51,329 --> 00:39:51,339 tonnes or something like that 1333 00:39:51,339 --> 00:39:53,970 tonnes or something like that 16 tonnes can you imagine how big the 1334 00:39:53,970 --> 00:39:53,980 16 tonnes can you imagine how big the 1335 00:39:53,980 --> 00:39:56,760 16 tonnes can you imagine how big the molecule one mole of water molecule one 1336 00:39:56,760 --> 00:39:56,770 molecule one mole of water molecule one 1337 00:39:56,770 --> 00:39:59,220 molecule one mole of water molecule one more one more water is 18 grams right 1338 00:39:59,220 --> 00:39:59,230 more one more water is 18 grams right 1339 00:39:59,230 --> 00:40:01,680 more one more water is 18 grams right just 18 grams one mole hydrogen is 2 1340 00:40:01,680 --> 00:40:01,690 just 18 grams one mole hydrogen is 2 1341 00:40:01,690 --> 00:40:04,620 just 18 grams one mole hydrogen is 2 grams so huge molecules as a matter of 1342 00:40:04,620 --> 00:40:04,630 grams so huge molecules as a matter of 1343 00:40:04,630 --> 00:40:07,079 grams so huge molecules as a matter of fact primarily in nucleus of the cell 1344 00:40:07,079 --> 00:40:07,089 fact primarily in nucleus of the cell 1345 00:40:07,089 --> 00:40:11,280 fact primarily in nucleus of the cell these are DNA DNA are found in nucleus 1346 00:40:11,280 --> 00:40:11,290 these are DNA DNA are found in nucleus 1347 00:40:11,290 --> 00:40:14,940 these are DNA DNA are found in nucleus of the cell remember in a cell there is 1348 00:40:14,940 --> 00:40:14,950 of the cell remember in a cell there is 1349 00:40:14,950 --> 00:40:17,910 of the cell remember in a cell there is a nucleus in the center so the DNA is 1350 00:40:17,910 --> 00:40:17,920 a nucleus in the center so the DNA is 1351 00:40:17,920 --> 00:40:20,579 a nucleus in the center so the DNA is found in the center now mostly outside 1352 00:40:20,579 --> 00:40:20,589 found in the center now mostly outside 1353 00:40:20,589 --> 00:40:23,040 found in the center now mostly outside of the nucleus in cytoplasm actually the 1354 00:40:23,040 --> 00:40:23,050 of the nucleus in cytoplasm actually the 1355 00:40:23,050 --> 00:40:25,020 of the nucleus in cytoplasm actually the outside of the nucleus of the cell is 1356 00:40:25,020 --> 00:40:25,030 outside of the nucleus of the cell is 1357 00:40:25,030 --> 00:40:27,450 outside of the nucleus of the cell is called cytoplasm now 1358 00:40:27,450 --> 00:40:27,460 called cytoplasm now 1359 00:40:27,460 --> 00:40:30,000 called cytoplasm now Storrs genetic information so the 1360 00:40:30,000 --> 00:40:30,010 Storrs genetic information so the 1361 00:40:30,010 --> 00:40:32,400 Storrs genetic information so the genetic information is stored in a DNA 1362 00:40:32,400 --> 00:40:32,410 genetic information is stored in a DNA 1363 00:40:32,410 --> 00:40:37,020 genetic information is stored in a DNA structure and the this information is 1364 00:40:37,020 --> 00:40:37,030 structure and the this information is 1365 00:40:37,030 --> 00:40:38,820 structure and the this information is carried from the nucleus of the cell 1366 00:40:38,820 --> 00:40:38,830 carried from the nucleus of the cell 1367 00:40:38,830 --> 00:40:42,930 carried from the nucleus of the cell into the cytoplasm by the RNA actually 1368 00:40:42,930 --> 00:40:42,940 into the cytoplasm by the RNA actually 1369 00:40:42,940 --> 00:40:48,510 into the cytoplasm by the RNA actually and the synthesis of the proteins 1370 00:40:48,510 --> 00:40:48,520 and the synthesis of the proteins 1371 00:40:48,520 --> 00:40:52,590 and the synthesis of the proteins particular proteins are become possible 1372 00:40:52,590 --> 00:40:52,600 particular proteins are become possible 1373 00:40:52,600 --> 00:40:54,390 particular proteins are become possible in the cytoplasm in in the cells 1374 00:40:54,390 --> 00:40:54,400 in the cytoplasm in in the cells 1375 00:40:54,400 --> 00:40:56,820 in the cytoplasm in in the cells specifies which proteins the cell can 1376 00:40:56,820 --> 00:40:56,830 specifies which proteins the cell can 1377 00:40:56,830 --> 00:40:58,920 specifies which proteins the cell can synthesize information is used in the 1378 00:40:58,920 --> 00:40:58,930 synthesize information is used in the 1379 00:40:58,930 --> 00:41:01,350 synthesize information is used in the protein synthesis outside of nucleus so 1380 00:41:01,350 --> 00:41:01,360 protein synthesis outside of nucleus so 1381 00:41:01,360 --> 00:41:03,510 protein synthesis outside of nucleus so this information actually carried out 1382 00:41:03,510 --> 00:41:03,520 this information actually carried out 1383 00:41:03,520 --> 00:41:06,360 this information actually carried out from the nucleus of the cell to the site 1384 00:41:06,360 --> 00:41:06,370 from the nucleus of the cell to the site 1385 00:41:06,370 --> 00:41:11,310 from the nucleus of the cell to the site applause by RNA let's see what else we 1386 00:41:11,310 --> 00:41:11,320 applause by RNA let's see what else we 1387 00:41:11,320 --> 00:41:13,470 applause by RNA let's see what else we have this is the structure of the 1388 00:41:13,470 --> 00:41:13,480 have this is the structure of the 1389 00:41:13,480 --> 00:41:16,730 have this is the structure of the nucleic acids in a nucleic acids we have 1390 00:41:16,730 --> 00:41:16,740 nucleic acids in a nucleic acids we have 1391 00:41:16,740 --> 00:41:19,500 nucleic acids in a nucleic acids we have nucleotides and these nucleotides are 1392 00:41:19,500 --> 00:41:19,510 nucleotides and these nucleotides are 1393 00:41:19,510 --> 00:41:24,090 nucleotides and these nucleotides are just like monomers like sugar in the 1394 00:41:24,090 --> 00:41:24,100 just like monomers like sugar in the 1395 00:41:24,100 --> 00:41:26,700 just like monomers like sugar in the carbohydrates polysaccharides and so on 1396 00:41:26,700 --> 00:41:26,710 carbohydrates polysaccharides and so on 1397 00:41:26,710 --> 00:41:29,250 carbohydrates polysaccharides and so on now what is this monomer or nucleotide 1398 00:41:29,250 --> 00:41:29,260 now what is this monomer or nucleotide 1399 00:41:29,260 --> 00:41:32,580 now what is this monomer or nucleotide let's look at that we have a phosphate 1400 00:41:32,580 --> 00:41:32,590 let's look at that we have a phosphate 1401 00:41:32,590 --> 00:41:36,000 let's look at that we have a phosphate group over here and we have a ribose 1402 00:41:36,000 --> 00:41:36,010 group over here and we have a ribose 1403 00:41:36,010 --> 00:41:41,550 group over here and we have a ribose sugar again here and then five carbon 1404 00:41:41,550 --> 00:41:41,560 sugar again here and then five carbon 1405 00:41:41,560 --> 00:41:44,370 sugar again here and then five carbon sugar and then we have what we call here 1406 00:41:44,370 --> 00:41:44,380 sugar and then we have what we call here 1407 00:41:44,380 --> 00:41:50,610 sugar and then we have what we call here a base unit any Nick nuclear base equal 1408 00:41:50,610 --> 00:41:50,620 a base unit any Nick nuclear base equal 1409 00:41:50,620 --> 00:41:52,200 a base unit any Nick nuclear base equal basis there are five different of those 1410 00:41:52,200 --> 00:41:52,210 basis there are five different of those 1411 00:41:52,210 --> 00:41:55,200 basis there are five different of those this one is a base unit I guess this is 1412 00:41:55,200 --> 00:41:55,210 this one is a base unit I guess this is 1413 00:41:55,210 --> 00:41:58,140 this one is a base unit I guess this is the other nine like this so now when we 1414 00:41:58,140 --> 00:41:58,150 the other nine like this so now when we 1415 00:41:58,150 --> 00:42:01,830 the other nine like this so now when we combine these this is monomer put them 1416 00:42:01,830 --> 00:42:01,840 combine these this is monomer put them 1417 00:42:01,840 --> 00:42:03,660 combine these this is monomer put them together from here from there and you 1418 00:42:03,660 --> 00:42:03,670 together from here from there and you 1419 00:42:03,670 --> 00:42:07,050 together from here from there and you see again that is the polymer and this 1420 00:42:07,050 --> 00:42:07,060 see again that is the polymer and this 1421 00:42:07,060 --> 00:42:10,050 see again that is the polymer and this part here the phosphate and here we have 1422 00:42:10,050 --> 00:42:10,060 part here the phosphate and here we have 1423 00:42:10,060 --> 00:42:13,710 part here the phosphate and here we have the sugar part ribose here we have the 1424 00:42:13,710 --> 00:42:13,720 the sugar part ribose here we have the 1425 00:42:13,720 --> 00:42:16,560 the sugar part ribose here we have the base and this is called the nuclear 1426 00:42:16,560 --> 00:42:16,570 base and this is called the nuclear 1427 00:42:16,570 --> 00:42:20,160 base and this is called the nuclear bases actually and there are six 1428 00:42:20,160 --> 00:42:20,170 bases actually and there are six 1429 00:42:20,170 --> 00:42:23,670 bases actually and there are six different bases as you will show you and 1430 00:42:23,670 --> 00:42:23,680 different bases as you will show you and 1431 00:42:23,680 --> 00:42:27,720 different bases as you will show you and this is the polymer so I see we simply 1432 00:42:27,720 --> 00:42:27,730 this is the polymer so I see we simply 1433 00:42:27,730 --> 00:42:30,960 this is the polymer so I see we simply have the nucleic acids polymer here now 1434 00:42:30,960 --> 00:42:30,970 have the nucleic acids polymer here now 1435 00:42:30,970 --> 00:42:32,610 have the nucleic acids polymer here now which one what what is the difference 1436 00:42:32,610 --> 00:42:32,620 which one what what is the difference 1437 00:42:32,620 --> 00:42:36,140 which one what what is the difference again is structure-wise between the 1438 00:42:36,140 --> 00:42:36,150 again is structure-wise between the 1439 00:42:36,150 --> 00:42:39,540 again is structure-wise between the deoxyribonucleic acid DNA and RNA this 1440 00:42:39,540 --> 00:42:39,550 deoxyribonucleic acid DNA and RNA this 1441 00:42:39,550 --> 00:42:41,150 deoxyribonucleic acid DNA and RNA this one is actually DNA 1442 00:42:41,150 --> 00:42:41,160 one is actually DNA 1443 00:42:41,160 --> 00:42:46,110 one is actually DNA this unit monomer DNA in RNA we have 1444 00:42:46,110 --> 00:42:46,120 this unit monomer DNA in RNA we have 1445 00:42:46,120 --> 00:42:47,580 this unit monomer DNA in RNA we have hydroxide here too 1446 00:42:47,580 --> 00:42:47,590 hydroxide here too 1447 00:42:47,590 --> 00:42:51,330 hydroxide here too so when we simply change the hydroxide 1448 00:42:51,330 --> 00:42:51,340 so when we simply change the hydroxide 1449 00:42:51,340 --> 00:42:53,930 so when we simply change the hydroxide to hydrogen it is called 1450 00:42:53,930 --> 00:42:53,940 to hydrogen it is called 1451 00:42:53,940 --> 00:42:56,490 to hydrogen it is called deoxyribonucleic acid which is the 1452 00:42:56,490 --> 00:42:56,500 deoxyribonucleic acid which is the 1453 00:42:56,500 --> 00:43:00,360 deoxyribonucleic acid which is the abbreviation DNA comes from now if I 1454 00:43:00,360 --> 00:43:00,370 abbreviation DNA comes from now if I 1455 00:43:00,370 --> 00:43:02,400 abbreviation DNA comes from now if I have an hydroxide here two hydroxide 1456 00:43:02,400 --> 00:43:02,410 have an hydroxide here two hydroxide 1457 00:43:02,410 --> 00:43:04,800 have an hydroxide here two hydroxide that becomes a right board nucleic acid 1458 00:43:04,800 --> 00:43:04,810 that becomes a right board nucleic acid 1459 00:43:04,810 --> 00:43:07,080 that becomes a right board nucleic acid which is the RNA that's the only 1460 00:43:07,080 --> 00:43:07,090 which is the RNA that's the only 1461 00:43:07,090 --> 00:43:10,350 which is the RNA that's the only difference between the ribose DNA and 1462 00:43:10,350 --> 00:43:10,360 difference between the ribose DNA and 1463 00:43:10,360 --> 00:43:13,470 difference between the ribose DNA and RNA very clearly here in this part right 1464 00:43:13,470 --> 00:43:13,480 RNA very clearly here in this part right 1465 00:43:13,480 --> 00:43:18,540 RNA very clearly here in this part right there and this is the polymer now the 1466 00:43:18,540 --> 00:43:18,550 there and this is the polymer now the 1467 00:43:18,550 --> 00:43:22,230 there and this is the polymer now the double helix that formed by the DNA by 1468 00:43:22,230 --> 00:43:22,240 double helix that formed by the DNA by 1469 00:43:22,240 --> 00:43:24,210 double helix that formed by the DNA by hydrogen bonding particularly hydrogen 1470 00:43:24,210 --> 00:43:24,220 hydrogen bonding particularly hydrogen 1471 00:43:24,220 --> 00:43:26,430 hydrogen bonding particularly hydrogen bonding between those bases nuclear 1472 00:43:26,430 --> 00:43:26,440 bonding between those bases nuclear 1473 00:43:26,440 --> 00:43:28,760 bonding between those bases nuclear bases nucleotides combine to form 1474 00:43:28,760 --> 00:43:28,770 bases nucleotides combine to form 1475 00:43:28,770 --> 00:43:31,770 bases nucleotides combine to form familiar double helix form of the 1476 00:43:31,770 --> 00:43:31,780 familiar double helix form of the 1477 00:43:31,780 --> 00:43:34,940 familiar double helix form of the nucleic acids this structure over here 1478 00:43:34,940 --> 00:43:34,950 nucleic acids this structure over here 1479 00:43:34,950 --> 00:43:38,450 nucleic acids this structure over here now hydrogen bonding dipole-dipole 1480 00:43:38,450 --> 00:43:38,460 now hydrogen bonding dipole-dipole 1481 00:43:38,460 --> 00:43:41,310 now hydrogen bonding dipole-dipole interactions and dispersion forces hold 1482 00:43:41,310 --> 00:43:41,320 interactions and dispersion forces hold 1483 00:43:41,320 --> 00:43:43,590 interactions and dispersion forces hold the double helix together but mainly 1484 00:43:43,590 --> 00:43:43,600 the double helix together but mainly 1485 00:43:43,600 --> 00:43:45,990 the double helix together but mainly hydrogen bonding here mainly hydrogen 1486 00:43:45,990 --> 00:43:46,000 hydrogen bonding here mainly hydrogen 1487 00:43:46,000 --> 00:43:50,220 hydrogen bonding here mainly hydrogen bonded these are adenine and thymine and 1488 00:43:50,220 --> 00:43:50,230 bonded these are adenine and thymine and 1489 00:43:50,230 --> 00:43:53,460 bonded these are adenine and thymine and so on like guanine guanine and adenine 1490 00:43:53,460 --> 00:43:53,470 so on like guanine guanine and adenine 1491 00:43:53,470 --> 00:43:55,470 so on like guanine guanine and adenine thymine hydrogen bonding between the 1492 00:43:55,470 --> 00:43:55,480 thymine hydrogen bonding between the 1493 00:43:55,480 --> 00:43:56,220 thymine hydrogen bonding between the nucleobases 1494 00:43:56,220 --> 00:43:56,230 nucleobases 1495 00:43:56,230 --> 00:43:58,500 nucleobases and the nuclear bases as this part here 1496 00:43:58,500 --> 00:43:58,510 and the nuclear bases as this part here 1497 00:43:58,510 --> 00:44:01,410 and the nuclear bases as this part here you see that part and that part there 1498 00:44:01,410 --> 00:44:01,420 you see that part and that part there 1499 00:44:01,420 --> 00:44:04,440 you see that part and that part there are five different nuclear bases I guess 1500 00:44:04,440 --> 00:44:04,450 are five different nuclear bases I guess 1501 00:44:04,450 --> 00:44:06,390 are five different nuclear bases I guess five different nuclear bases yes 1502 00:44:06,390 --> 00:44:06,400 five different nuclear bases yes 1503 00:44:06,400 --> 00:44:10,920 five different nuclear bases yes now complementary bases pairs form ideal 1504 00:44:10,920 --> 00:44:10,930 now complementary bases pairs form ideal 1505 00:44:10,930 --> 00:44:13,890 now complementary bases pairs form ideal hydrogen partners hydrogen bonding 1506 00:44:13,890 --> 00:44:13,900 hydrogen partners hydrogen bonding 1507 00:44:13,900 --> 00:44:16,790 hydrogen partners hydrogen bonding partners for example alanine and thymine 1508 00:44:16,790 --> 00:44:16,800 partners for example alanine and thymine 1509 00:44:16,800 --> 00:44:19,770 partners for example alanine and thymine Ryan makes a hydrogen bonding and this 1510 00:44:19,770 --> 00:44:19,780 Ryan makes a hydrogen bonding and this 1511 00:44:19,780 --> 00:44:22,470 Ryan makes a hydrogen bonding and this is cytosine and guanine makes it ideal 1512 00:44:22,470 --> 00:44:22,480 is cytosine and guanine makes it ideal 1513 00:44:22,480 --> 00:44:24,990 is cytosine and guanine makes it ideal hydrogen bonding and these hydrogen bond 1514 00:44:24,990 --> 00:44:25,000 hydrogen bonding and these hydrogen bond 1515 00:44:25,000 --> 00:44:28,290 hydrogen bonding and these hydrogen bond ends makes this helix structure possible 1516 00:44:28,290 --> 00:44:28,300 ends makes this helix structure possible 1517 00:44:28,300 --> 00:44:30,960 ends makes this helix structure possible helix structure